‘Tissue chips’ could replace animal studies, UW-Madison researchers say

(Jamie) Thomson, who first grew human embryonic stem cells in a lab in 1998 and co-discovered a way to reprogram mature cells to their embryonic state in 2007, is working with researchers across campus on … creating “tissue chips” — clusters of interacting cells that mimic specific organs, such as a model of a developing brain. Using stem cells, miniature scaffolds and sophisticated computer programs, they’re crafting prototypes that could someday replace animal testing for drugs and serve as screening tools for environmental toxins.