Planning to indulge in a caramel apple this fall? You may want to eat it fresh or at least make sure it’s refrigerated, a new study suggests. Researchers from the University of Wisconsin-Madison’s Food Research Institute found that caramel apples punctured with dipping sticks and left unrefrigerated over the course of a couple of weeks may harbor Listeria monocytogenes, a bacterium linked to a serious infection that can cause fever, headaches, gastrointestinal symptoms and sometimes death.