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How the leading coronavirus vaccines made it to the finish line

Some scientists believed from the start that it would be possible to repurpose this basic cellular function for medicine. In 1990, a Hungarian-born scientist at the University of Pennsylvania, Katalin Kariko brashly predicted to a surgeon colleague that his work would soon be obsolete, replaced by the power of messenger RNA therapies. That same year, a team at the University of Wisconsin startled the scientific world with a paper that showed it was possible to inject a snippet of messenger RNA into mice and turn their muscle cells into factories, creating proteins on demand.