A skin sample from Helen Eckert, transformed into a colony of heart cells in a UW-Madison lab, could give scientists clues to what causes Long QT Syndrome, a genetic heart disease. Researchers reprogrammed her skin cells into induced pluripotent stem cells, or iPS cells, containing the genetic mutation she carries that causes Long QT Syndrome. The iPS cells were coaxed into heart cells, also with the mutation. The process involved an iPS cell method developed by UW-Madison stem cell pioneer James Thomson.
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