Skip to main content

Category: Research

Bird flu breakthrough at UW

Capital Times

Researchers from the UW-Madison have identified a key step that the avian flu virus would have to take to be able to transmit easily from person to person — which could result in an international pandemic.

The researchers, led by internationally known virologist Yoshihiro Kawaoka, have identified a single change in a viral protein that facilitates the virus’ ability to infect the cells of the upper respiratory system in mammals.

By adapting to the upper respiratory system, the virus could infect a wider range of cell types and would be more easily spread.

Disputed stem cell patents amended (The Scientist, UK)

The Scientist

The Wisconsin Alumni Research Foundation (WARF) has filed three supplemental amendments to its disputed embryonic stem cell claims, which are undergoing re-examination by the US Patent Office.

But the changes will have little impact on the point at issue, which is whether the techniques described were original enough to be patented, according to William L. Warren, an intellectual property lawyer with Sutherland Asbill & Brennan in Atlanta.

Bird flu virus mutating into human-unfriendly form (Reuters)

NEW YORK (Reuters) – The H5N1 bird flu virus has mutated to infect people more easily, although it still has not transformed into a pandemic strain, researchers said on
Thursday.

The changes are worrying, said Dr. Yoshihiro Kawaoka of the University of Wisconsin-Madison.”We have identified a specific change that could make bird flu grow in the upper respiratory tract of humans,” said Kawaoka, who led the study.

UW-Madison researchers wage war on cancer stem cells

Wisconsin State Journal

Dr. John Kuo, a UW Hospital brain surgeon, knows all too well what frequently happens after he removes a cancerous tumor from a patient.

The tumor grows back, despite post-surgery radiation and chemotherapy.

Researchers have identified a new reason for such recurrences: cancer stem cells.

Studies endorse ‘virtual colonoscopy’

USA Today

Having an X-ray to look for signs of colon cancer may soon be an option for those who dread the traditional scope exam. Two of the largest studies yet of “virtual colonoscopy” show the experimental technique works just as well at spotting potentially cancerous growths as the more invasive method.

Quoted: Dr. Perry Pickhardt, one of the researchers at the University of Wisconsin Medical School who are reporting the results of their study in Thursday’s New England Journal of Medicine.

‘Virtual’ Colonoscopy an Effective Option: Study (HealthDay News)

A new study supports the effectiveness of an innovative form of colonoscopy that relies on a CT scanner that’s sent through a patient’s colon.

When it comes to detecting polyps that might become malignant, this so-called “virtual colonoscopy” is just as effective as the traditional approach of using a fiber-optic device, explained study lead Dr. David Kim, assistant professor of radiology at the University of Wisconsin.

Studies: New colon cancer test accurate, less invasive (AP)

Chicago Tribune

NEW YORK – Having an X-ray to look for signs of colon cancer may soon be an option for those who dread the traditional scope exam.

Two of the largest studies yet of “virtual colonoscopy” show the experimental technique works just as well at spotting potentially cancerous growths as the more invasive method.

“This is ready for prime time,” said Dr. Perry Pickhardt, one of the researchers at the University of Wisconsin Medical School who are reporting the results in Thursday’s New England Journal of Medicine.

Aysha Akhtar, M.D.: Evidence shows animal research is a waste

Capital Times

Dear Editor: In addition to the ethical issues raised by animal research, more and more members of the medical research community are calling attention to the fundamental problems with animal experiments (“Doc: Testing on animals obsolete”).

As a neurologist and public health specialist, I know there is ample evidence that underscores the urgent need to move away from using animals in research.

China acquires a taste for cheese, whey

Milwaukee Journal Sentinel

The Babcock Institute for International Dairy Research and Development at the University of Wisconsin-Madison has helped train Chinese farmers in some of the latest dairying techniques. More than 700 model dairy farms have been established around Beijing and Tianjin, with 280,000 cows, according to the Chinese government.

Institutes to share research incubator

Milwaukee Journal Sentinel

A planned $150 million research and business incubator in Madison will be housed in one building, with two institutes representing the public and private sectors each having their own lab areas.

Architectural renderings unveiled Monday on the University of Wisconsin-Madison campus showed a building with three towers.

UW receives energy grant

Badger Herald

The University of Wisconsin received more than $6.6 million last week from the federal government in an effort to jumpstart alternative fuel research.

Madison firm wins grant for cancer drug

Milwaukee Journal Sentinel

A grant received by Centrose LLC highlights the growing cluster of companies in Madison aiming to develop new drugs in areas like cancer and neurodegenerative and heart disease.

Centrose said Friday it has received a $160,000 grant from the National Cancer Institute to continue developing its lead anti-cancer drug program. The company, based in Madison, is using sugar chemistry to work with a variety of existing and failed drugs to make them less toxic and more effective.

Many University of Wisconsin-Madison researchers have received grants from the cancer institute, but more companies in the area are getting them now, said Tom Still, president of the Wisconsin Technology Council.

VET’S WORK DOES DOUBLE DUTY

Wisconsin State Journal

Her patients can ‘t tell Dr. Ruthanne Chun what ‘s wrong with them.

The dogs she sees at UW-Madison ‘s School of Veterinary Medicine don ‘t explain when their front left leg hurts or they feel run-down or they have a suspicious lump.

Rick Marolt: Animal research no use against human diseases

Capital Times

Dear Editor: At a public debate on Sept. 26, Dr. Ray Greek made the argument, supported by much data and clear logic, that animal research does not and cannot help us cure human disease or find safe and effective drugs for humans. His debate opponent, Eric Sandgren from the UW-Madison, failed to present a meaningful rebuttal.

Education, wealth shown to affect health (Reuters Health)

NEW YORK — The more educated you are, the less likely you are to become chronically ill or disabled, but the amount of money you make plays a bigger role in whether your illness progresses, a new study shows.

Based on the findings, the most effective single policy strategy for improving health might be to make higher education more accessible, Dr. Pamela Herd of the University of Wisconsin-Madison, the study’s lead author, told Reuters Health.

Alternative reality: UW prof touts computer game learning

Wisconsin Technology Network

Madison, Wis. – In an era of standardized testing, the idea of introducing computer games into the classroom might be tantamount to driving a square peg into round hole.

Even though parents and educators increasingly see the value of computer game learning, the powers who drive education policy are either still too wedded to the type of learning that prepared students for the industrial age, or they think teaching with computer games is too radical to suggest at the moment – even if they know the digital world is creating a new paradigm for education.

The potential value of computer game education, and the counterintuitive thinking it requires, has not been lost on University of Wisconsin-Madison professor David Williamson Shaffer, author of â??How Computer Games Help Children Learn.â?

Curiosities: 8,000 POWs were held in Wisconsin camps

Wisconsin State Journal

Q. During World War II, Japanese and Germans prisoners of war were detained in camps in Wisconsin. Where were the Wisconsin camps, how long were these people held and what happened to them after the war?
A. More than 3,000 Japanese and 5,000 German POWs were held in Wisconsin during World War II, said Geraldine Strey, reference librarian and archivist at the Wisconsin Historical Society.

Doc: Testing on animals obsolete

Capital Times

The use of animals for drug testing and disease research is flawed science and should be abandoned, the leader of an advocacy group says.

“It’s like using a canoe to cross the Pacific Ocean. Yes, it was done at one time, but today we use airplanes,” said Dr. Ray Greek, president of Americans for Medical Advancement and a retired anesthesiologist and expert in pain management living in California. “Today we are studying humans at the level where the differences between species outweigh the similarities.”

Greek debated with UW animal researcher Eric Sandgren on the merits of using animals in scientific research before a crowd of about 175 at the Wisconsin Historical Society building Wednesday night.

Research grants highlight value of UW-Madison

Wisconsin State Journal

Two health-related research grants won by UW-Madison show yet again the university’s immense value to people in Wisconsin and in the nation.
Republican lawmakers negotiating the state budget should keep that in mind. Shortchanging the UW System would shortchange the public.

Study: Few do not form racial prejudices (UPI)

United Press International

U.S. researchers found just 7 percent of respondents do not have the usual human tendency to favor one’s own group and not form racial prejudices.

Their study, published in the journal Psychological Science, found the 7 percent of people that showed no racial bias differed from biased individuals in a fundamental way — they also were less likely to form negative emotional associations in general.

Robert Livingston of Northwestern University and Brian Drwecki of the University of Wisconsin asked white college students to do tasks that repeatedly paired unfamiliar Chinese characters with positive or negative images such as puppies or snakes. The results showed non-biased individuals were less likely than biased individuals to acquire negative emotions toward the character paired with negative pictures.

Debate set Wednesday on animal research

Capital Times

Should animals be used by UW-Madison researchers? Are they a reliable predictor of diseases and their cures for human beings?

Two highly respected experts on the subject will tackle that issue in a debate sponsored by The Capital Times at 7 p.m. Wednesday in the auditorium of the Wisconsin Historical Society building on the UW’s Library Mall.

Runoff blamed for deformed frogs

Wisconsin State Journal

It was back in 1995 that a group of Minnesota middle schoolers shocked the scientific community when they returned from a field trip to report that more than half the frogs they’d captured had major deformities.

Some had five or more hind legs or even no legs at all.

But in the investigations that followed, it quickly became clear that cases of deformed amphibians went far beyond that Minnesota pond and were actually fairly widespread across the U.S.

Those who stay in school, stay healthier (South Florida Sun-Sentinel)

Both education and income can determine whether a person will remain healthy, but those who stay in school longer have the best odds, largely because education so strongly influences income, say the authors of a new study.

“Those with less education are more likely to develop health problems and those with low incomes who already have health problems are more likely to see their health worsen,” said lead author Pamela Herd, a University of Wisconsin-Madison sociologist.

UW geologist leads research team on deep-sea expedition

Daily Cardinal

Aboard a newly built research vessel, UW-Madison geologist Harold Tobin and a team of scientists set sail Friday on an eight-week expedition to drill, sample and study a fault zone off the coast of Japan.

The international research expedition, which is part of the Integrated Ocean Drilling Program, will look into understanding what causes earthquakes at deep-sea fault lines.

Taking the sting out of drug application

Wisconsin State Journal

A small Madison biotechnology company called Ratio is working to commercialize a painless way to administer drugs. The system, which is touted as being simpler and less expensive than others on the market, was invented by David Beebe, a UW-Madison professor of biomedical engineering, and his colleagues at UW-Madison and the University of Illinois.

Ocean drilling: In the zone (Nature)

Nature

When it comes to natural disasters, the Japanese government is good with numbers. It expects, for instance, a magnitude-8.1 quake to strike in the next 30 years with an epicentre in the Nankai trough â?? a depression in the sea-floor 100 kilometres off the country’s east coast. And when it hits, it is likely to kill between 12,000 and 18,000 people.

The Nankai trough lies in a subduction zone, a perilous region in which one tectonic plate dives under another, building up the sort of rock strain that can unleash the world’s most powerful earthquakes. All earthquakes with a magnitude of greater than 9 have occurred in these zones. And although the next earthquake at Nankai is not expected to be quite this big, the region could prove key in understanding why earthquakes in subduction zones release such vast amounts of energy.

Quoted: Harold Tobin of the University of Wisconsin in Madison, the project’s other chief scientist.

A clear-cut case of conservation?

Daily Cardinal

Even before the sun eases up past the horizon, the Lakeshore Path is dotted with runners and bikers hoping to get the path to themselves before itâ??s filled with families and leisurely walkers, looking for the first glinting red leaves of autumn. A few people walk briskly in the crisp air, swinging briefcases and backpacks, on their way to work at the Capitol or to campus for school. Golden light sifts its way through the trees near the Lakeshore dorms, revealing a large pair of bulldozers near a huge pile of brush.

Dave Zweifel: Animal research is hot topic for debate

Capital Times

Virtually nothing stirs up the human emotions more than the practice of using animals in medical and scientific experiments that have become so commonplace on many of our university campuses.

The University of Wisconsin-Madison is no exception. Scientists there experiment on everything from pigs to monkeys in researching the causes and cures for human disease.

UW-Madison receives $7.2 million stem cells ALS grant

Wisconsin State Journal

UW-Madison stem-cell scientists have received a $7.2 million grant from the National Institutes of Health to study rats with Lou Gehrig’s disease.

About 30,000 Americans have the disease, also known as amyotrophic lateral sclerosis, or ALS. The progressive condition, usually fatal within a few years after diagnosis, weakens muscles and eventually makes people unable to breathe.

UW Scientists Head Out To Sea (AP)

MADISON, Wis. (AP) – A Wisconsin scientist will set sail Friday to study earthquakes off Japan.

University of Wisconsin-Madison geologist Harold Tobin is part of a team that will investigate deep oceanic faults in the Nankai Trough. Such faults are responsible for creating tsunamis.

Tobin and the team will launch their research vessel from Shingu Port in Japan.

The expedition calls for deep-sea drilling.

It’s expected to last eight weeks.

Institute shuts down UW lab

Badger Herald

The University of Wisconsin allowed a star researcher to study material that could be used to produce the Ebola virus in a lab less secure than whatâ??s required under federal guidelines.

Early ebola research at UW creates controversy

Capital Times

The UW-Madison conducted research on the deadly Ebola virus in 2005 and 2006 in a lower-level security facility than is recommended until the National Institutes of Health told the university to stop.

John Hammond, director of the Sunshine Project, a watchdog group for biological research, said Wednesday that researchers at the University of Wisconsin made and manipulated copies of the entire Ebola virus genome without proper safety precautions.

Ebola study stopped

USA Today

The University of Wisconsin-Madison allowed a star researcher to study genetic material that could produce the Ebola virus in a lab less secure than required under federal guidelines, officials said Wednesday. The study stopped last fall after a federal health official told the university the material must be contained in the most secure type of lab, a Biosafety Level 4.

UW-Madison stops Ebola virus study after warning

Wisconsin State Journal

UW-Madison allowed a star researcher to study material that could be used to produce the Ebola virus in a lab less secure than what’s required under federal guidelines.

The study was stopped last fall after a National Institutes of Health official told the university the material must be contained at labs with the highest level of security, or Biosafety Level 4.

Health institute awards UW Med. School $41 mil.

Daily Cardinal

The National Institutes of Health annoaunced Tuesday it has awarded UW-Madisonâ??s School of Medicine and Public Health a $41 million grant, one of the largest grants in the schoolâ??s history.

The grant will funnel into the universityâ??s new Institute for Clinical and Translational Research. â??This is a highly visible, highly covetous award given to only the most elite institutions in the country,â? said Robert Golden, dean of the UW School of Medicine and Public Health.

UW gets grant for $41 million

Wisconsin State Journal

Many patients don ‘t do what science says they should, from people at risk for heart disease taking aspirin to prevent heart attacks to men taking drugs to stave off osteoporosis, a bone disease.

A $41 million federal grant awarded to UW-Madison aims to bridge such gaps by improving the way campus discoveries are spread to the public.

UW wins $41M health grant

Capital Times

The National Institutes of Health has awarded the UW-Madison Medical School a $41 million grant to help get medical research findings to patients more quickly.

The goal of the effort, known as translational research, is to move biomedical and health sciences discoveries into practical use in doctors’ offices, clinics and hospitals, where the knowledge can be used more rapidly and effectively to improve people’s health, officials said.

UWM raises ante on acreage for Innovation Park

Milwaukee Journal Sentinel

The University of Wisconsin-Milwaukee’s proposal for a new engineering school and research park would require buying some 83 acres of Milwaukee County Grounds property near Highway 45 and Swan Blvd., UWM Chancellor Carlos Santiago said Monday.

Wisconsin private sector on board for Great Lakes Bioenergy Research Center

Wisconsin Technology Network

Milwaukee, Wis. – The private sector’s interest level in the Great Lakes Bioenergy Research Center is extremely high and includes a diversity of interests that are engaged in the project, according to the University of Wisconsin-Madison dean who helped write a successful grant proposal to fund the center.

Molly Jahn, dean of UW-Madison’s College of Agricultural and Life Sciences, said the recent five-year, $125 million Department of Energy grant award that established the research center will produce economic and environmental benefits for Wisconsin and the Midwest – something the private sector is keenly aware of.

Wisconsin still No. 1 in booze use. Leads nation in binge drinking (AP)

Capital Times

MILWAUKEE — When he gives lectures on how alcohol harms Wisconsin communities, Dr. Paul Moberg starts by showing an editorial cartoon he calls “sobering.”

The 1994 cartoon by Green Bay Press-Gazette cartoonist Joe Heller shows University of Wisconsin-Madison mascot Bucky Badger in front of a blackboard bearing a series of ignominious state rankings: Wisconsin leads the nation in binge drinking and in percentage of adult drinkers.

“Hello,” the caption says, “My name is Bucky and I have a drinking problem.”

Why do some carry the cystic fibrosis mutation?

Wisconsin State Journal

Why do 10 million Americans carry the genetic mutation that causes cystic fibrosis, even though they don’t have the frequently fatal lung disease?

The answer could lie in 2,500-year-old bones from Europe being tested at the State Laboratory of Hygiene.

An international effort, led by Dr. Phil Farrell, a pediatric pulmonologist from UW-Madison, is analyzing bones from ancient Celtic people.

Adam Mertz: Now, Badgers have a will and a whey

Capital Times

A decade or so ago, the University of Wisconsin put its stamp on a sports drink that was meant to become synonymous with its athletic department, and become marketable to a large-scale audience.

But Badger Max not only failed to unseat its close cousin Gatorade, which was developed at the University of Florida in the mid-1960s thanks to the curiosity of an assistant football coach, it was far from a hit at home.

UW biotech to benefit soon

Badger Herald

University of Wisconsin biotechnology will soon have the capability to accomplish unprecedented feats, thanks to $23.6 million in recent investments in a Madison company.

Don’t duplicate health schools

Wisconsin State Journal

Why should Wisconsin invest millions of dollars to build and operate a UW school of public health in Milwaukee, when a school of public health already exists at UW-Madison?

That question should prompt lawmakers to delete from the state budget a proposal to spend $500,000 on planning for a UW-Milwaukee school of public health and to deny the university ‘s request to start hiring faculty and staff.