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Category: Research

Groups to respond to WARF’s patent defense (The Business Journal of Milwaukee)

The two consumer groups that successfully challenged three, broad stem cell patents held by the University of Wisconsin-Madison’s patent licensing arm said that it will make a “substantive response” to the university group’s defense of the patents.

Acting on re-examination requests by the Foundation for Taxpayer and Consumer Rights and the Public Patent Foundation, the U.S. Patent and Trademark Office in early April rejected all claims on three patents held by the Wisconsin Alumni Research Foundation. WARF had two months to respond.

WARF to appeal cancellation of stem-cell patents (WPR)

Wisconsin Public Radio

(MADISON) The Wisconsin Alumni Research Foundation or WARF is challenging the federal governmentâ??s preliminary rejection of three stem cell patents. In April, the U.S. Patent and Trademark Office announced it would throw out the patents because discoveries made by University of Wisconsin researcher James Thomson were â??obvious,â? given earlier research. (Fifth item.)

UW riled over move on patents (AP)

The University of Wisconsin’s research arm challenged the federal government’s rejection of its patents covering human embryonic stem cell research on Thursday, defending researcher Jamie Thomson’s work as a “landmark invention.”

The California-based Foundation for Taxpayer and Consumer Rights and others are challenging patents that covr discoveries by Thomson, who was the first to grow and isolate human embryonic stem cells in 1998.

(Appears in 6/1/07 Capital Times)

Checking for aliens under rocks

Wisconsin State Journal

Clark Johnson will be spending the next several years of his career as a UW-Madison geologist doing something he never really dreamed of doing — looking for extraterrestrial life.

Debate rages over UW stem-cell patents

Wisconsin State Journal

James Thomson’s breakthrough in growing human embryonic stem cells in 1998 is worthy of the patents he received because no researchers had done what he did, the Wisconsin Alumni Research Foundation said Thursday, in response to the federal government’s preliminary rejection in March of three patents.

WARF questions relevancy of documents used to uphold patent challenge

Wisconsin Technology Network

Madison, Wis. – Claiming that patents and publications used to uphold a challenge to its stem cell patents are irrelevant to the isolation and proliferation of human embryonic stem cells, the Wisconsin Alumni Research Foundation has filed a response refuting an initial determination by the U.S. Patent and Trademark Office.

Those observations on relevancy, made by Carl Gulbrandsen, managing director of WARF, were supported by Dr. Colin Stewart, a stem cell researcher at the Institute of Medical Biology in Singapore.

UW challenges rejection of patents

Milwaukee Journal Sentinel

With its patents on the stem cell work of University of Wisconsin-Madison professor James Thomson preliminarily rejected, the foundation that helps shepherd the school’s research discoveries to market fired back Thursday, saying the rejection was wrong on multiple counts.

UW-Madison lands $6.5M NASA grant (The Business Journal of Milwaukee)

The University of Wisconsin-Madison said Thursday that it has been awarded a $6.5 million grant from NASA to join a collaboration studying the origins and evidence of life on Earth.

With the National Aeronautics and Space Administration funds, Wisconsin researchers will become part of NASA’s Astrobiology Institute. The Institute focuses on the hunt for extraterrestrial life and early life on Earth by developing techniques and instruments to read the chemical signatures living organisms leave in rocks and minerals.

Brainpower called key to prosperity

Milwaukee Journal Sentinel

The Milwaukee region, once known as the “machine shop to the world,” must remake itself as the industrial “design shop of the world” if it is to compete in a landscape transformed by global economic forces, civic leaders said Wednesday in unveiling the Milwaukee 7s strategic economic plan.

The report by the seven-county economic development group said southeastern Wisconsins future hinges on its engineering talent, research-and-development capacity, its universities and its collective impulse to generate products and ideas.

Wineke: Warming up to nuclear power

Wisconsin State Journal

If you’re lucky enough to live long enough, sometimes the world will come around to your way of thinking.

Professor Max Carbon retired from the UW-Madison nuclear engineering faculty 15 years ago and during both his working and retirement careers has been a rather lonely voice touting the virtues of nuclear power.

Veterinarians Learn To Test For Deadly Fish Virus

WISC-TV 3

Wisconsin is leading the way in the cutting-edge science, WISC-TV reported. A 7-year-old University of Wisconsin Veterinary School and state Agriculture Department course is now teaching high-level animal health experts, public and private, how to test for VHS.Experts said that it’s important to collect a good tissue sample from some tiny fish organs.”Because of where the virus likes to live, they prefer that we get those organs because it’s more likely that they’ll be able to isolate virus from it,” said Patricia Fox, who works for veterinary services for the USDA in Madison.UW veterinarian Michael Maroney and Indiana Board of Animal Health veterinarian Jennifer Strasser said that VHS testing is easier said than done. But they said that learning the correct process is crucial, saying they need all the tools they can muster to battle their biggest fish threat ever.

Legislature should look to Wisconsin’s natural energy advantages

Wisconsin Technology Network

Madison, Wis. – Will Wisconsin join the biofuels parade as the marketplace elephant passes by – or follow behind with a shovel?

That question was raised by state Sen. Bob Jauch, the veteran Democrat from Poplar, during Tuesday’s Capitol debate over the state’s 2007-2009 budget bill. So far, the answer isn’t pretty.

Cook: A critical juncture for Giuliani (National Journal)

MSNBC.com

University of Wisconsin political scientist Charles Franklin has his own Web site on polling, Political Arithmetik, and partners on a second site, pollster.com.

These are two must-visit sites for those fascinated with political polling. On both sites, Franklin regularly publishes updated graphs of his “trend estimator,” something more sophisticated than, but similar to, a moving average showing the relative strengths of each presidential candidate in recent national polls.

Entire state would benefit from national lab siting (Racine Journal Times)

Racine Journal Times

Sigh. We hate to see missed opportunities and Wisconsin looks like it might miss out on a good one.

The state and the University of Wisconsin-Madison are making a pitch to have a high security national agro- and bio-defense lab just southeast of Madison, but the bid is being undercut by local opposition.

Town of Dunn residents are opposing the $450 million project out of safety concerns and worries that it won’t fit in with the quiet and rural character of their town.

They’ve started a letter writing campaign, convinced the Dane County Board and town board to oppose it and even have an opposition sampler on the town’s web site soliciting petitions and offering yard signs.

UW Professor: Blame your allergies on society, too

Racine Journal Times

Think again when you have your allergic sneezes this year. Think about more than medicine and youâ??ll please Gregg Mitman.

He wants you to think about the environment you inhabit and how what weâ??ve built has made you sick. In his book â??Breathing Space: How Allergies Shape Our Lives and Landscapesâ? published this month by Yale University Press, Mitman explores the ecology of allergies, in other words, what humans have done to harm themselves.

UW, town in tiff over lab turf

Milwaukee Journal Sentinel

Wisconsin is in the running to land the nations new high-security lab that will study foot-and-mouth disease, bird flu and other deadly animal illnesses.

The $450 million lab is projected to employ at least 300 people and generate more short-term jobs to build it. The National Bio- and Agro-Defense Lab would dovetail with the University of Wisconsin-Madison’s expertise in animal and human health studies and help serve the states agricultural industry, supporters say.

But there’s a snag with the labs proposed location.

UW student contest advances biomedicine

Capital Times

The inaugural Tong Biomedical Engineering Design Award competition for students at the University of Wisconsin-Madison yielded devices designed for the use of radiologists, audiologists and those treating sports-related injuries.

All of the devices were designed by UW-Madison biomedical engineering students. The competition earlier this month at UW-Madison involved nearly 150 biomedical engineering students. First-place awards were given to teams from the sophomore, junior and senior classes.

Stem cell and regenerative medicine center to aid education and commerce

Wisconsin Technology Network

Madison, Wis. – The coordination of the companion disciplines of stem cell research and regenerative medicine will be the focus of a new interdisciplinary center being established at the University of Wisconsin-Madison, but it is also being developed with the biotechnology industry in mind.

The center initially will operate in â??virtualâ? space, and will serve as a central entity under which the UW-Madison campus can strengthen its stem cell research, training, and education programs.

UW Launches Virtual Stem Cell Center on Day Dolly Would Have Turned 10

WKOW-TV 27

Thursday would be the 10th Birthday for the cloned sheep known as Dolly.

Ian Wilmut was the scientist who created the cloned sheep 10 years ago.

He spent the anniversary in Madison to talk about the stem cell and regenerative medicine center being built back in Edinburgh, Scotland – where he is from.

He says stem cell research has come a long way since the inception of Dolly, – he says there’s still a long way to go but he thinks the end results will be great.

MATC teaches stem cell skills

Capital Times

Mary Troestler is excited and proud to be working with stem cells at Madison Area Technical College.

….MATC’s 20-year-old biotechnology program recently received human embryonic stem cells from WiCell through an agreement with the Wisconsin Alumni Research Foundation so students can learn lab techniques relating to the culture of stem cells.

New UW grads enter work force armed with sustainable skills, goals

Capital Times

A new corporate emphasis on a “triple bottom line” is leading to new and varied jobs for University of Wisconsin-Madison graduates, a trend that is expected to grow rapidly.

“The traditional bottom line is that a company has to perform well financially, but now that company has to have a good environmental performance and a good social responsibility record as well,” said Dan Anderson, a professor in the UW School of Business who also teaches at the Nelson Institute for Environmental Studies.

Dolly creator sees end to cloning

Wisconsin State Journal

The birth of the cloned sheep Dolly rocked the scientific and ethical worlds 10 years ago by showing that cloning was possible.

But her biggest legacy may be that the controversial process of using cloning to try to produce customized stem cells for patients could become obsolete, according to the scientist who created her.

UW to open stem-cell center

Wisconsin State Journal

UW-Madison may be known worldwide for stem-cell research, but the campus has lacked an organized way to get its stem-cell scientists to share lab equipment, train new researchers, educate the public and garner federal grants, campus authorities say.

Obesity starts in infancy (San Antonion Express-News)

The path to diabetes and heart disease may begin in infancy for children in poor urban households, according to a nationwide study released this year that suggests as many as one-third of 3-year-olds in low-income families may be overweight or obese.

The study found the problem is even more pronounced in Hispanic households.

Researchers looked at several factors, such as television viewing hours, breast feeding and weight of the mother, and couldn’t explain why Hispanic children are more at risk, said Rachel Tolbert Kimbro, a researcher from the University of Wisconsin’s Institute for Research Into Poverty.

Rick Bogle: UW should be open with research danger

Capital Times

Dear Editor: In his May 12 letter to the editor, Dr. James W. Tracy asserts that Dr. Yoshihiro Kawaoka has not worked with “live, infectious” 1918 Spanish flu virus on the Madison campus.

….In the spirit of transparency, the university should make available on its Web site all research protocols involving deadly airborne agents and explain the methods being used to contain them and safeguard the public’s health.

Study: Meditation Can Improve Focus

Wisconsin State Journal

The ability to pay attention may not have a fixed capacity, as many people believe, says a UW-Madison study suggesting that meditation can improve people’s knack for focusing their minds.

Biologist Who Cloned Dolly To Speak In Madison

Wisconsin State Journal

Ian Wilmut, the Scottish biologist who created Dolly the cloned sheep, will give a public lecture at 7 p.m., Thursday at the Overture Center.
“Cloning in the 10 Years Since Dolly” will explore the science of somatic cell nuclear transfer, or cloning, and its potential for biomedical research.

No Place Like Om: Meditation training puts oomph into attention

Science News

Intensive meditation training does more than foster inner peace and relaxation. Mental practice of this type boosts control over attention and expands a person’s ability to notice rapidly presented items, at least during a laboratory test.

The new results demonstrate that mental resources devoted to attention can be amplified through mental training, say psychologist Richard J. Davidson of the University of Wisconsinâ??Madison and his colleagues

Madison stem cell company receives $1 million from state

La Crosse Tribune

MADISON, Wis. – A Madison stem cell company developing ways to screen drugs for side effects will receive $1 million in a grant and a loan from the state to help get started, Gov. Jim Doyle said Monday.

Stemina Biomarker Discovery, Inc., is trying to commercialize discoveries made by University of Wisconsin-Madison stem cell researcher Gabriela Cezar, the companyâ??s co-founder and chief scientific officer.

The company is trying to build a library of biomarkers to help companies screen drugs and drug candidates for potentially toxic side effects. Biomarkers are the signals that stem cells give off when exposed to a certain drug or disease.

$1M state boost will support research on drug toxicity

Capital Times

A Madison stem cell start-up company will get a $1 million boost from the state, Gov. Jim Doyle announced this morning.

Top University of Wisconsin-Madison researcher Gabriela Cezar co-founded Stemina Biomarker Discovery Inc. in November with Beth Donley, the former executive director of WiCell, the stem cell subsidiary of the Wisconsin Alumni Research Foundation.

With the aid of two WARF stem cell patents, the company is developing ways to help drug manufacturers screen drugs for toxicity. The aim is to save millions of dollars in drug development costs by developing a library of biomarkers that discover toxins in the early stages of pharmaceutical development.

Can Madison clean its lakes?

Wisconsin State Journal

Steve Carpenter, a UW-Madison limnologist, said people should keep in mind the history of the lakes and understand that improvements are likely to take a long time, even with measures such as the phosphorus bans. Some people would find it hard to believe, he said, that all direct sources of lake pollution, including human waste, were not eliminated until the 1970s. In fact, Carpenter said, the lakes are much cleaner than they were in the 1950s when they were the repository for raw human sewage.

Stem cell firm gets $1 million

Milwaukee Journal Sentinel

Stemina Biomarker Discovery Inc. will receive $1 million in loans and grants from the state, Gov. Jim Doyle will announce today.

The Madison company was founded in November by a former top executive at the University of Wisconsin-Madison’s patenting arm and a high-profile UW scientist. It is the third company started in the state that uses embryonic stem cells.

Odds high, funds sparse for stem cell researchers (The Boston Globe)

Boston Globe

For all the hype and hope surrounding stem cell research, most of the companies trying to develop treatments from these powerful cells live in a place Governor Deval Patrick this week called the “valley of death.” It is a harsh place where neither the federal government nor private investors provide much support and small firms with limited funding struggle to figure out how to harness stem cells’ extraordinary power.

Power Nap Device In Development (LiveScience.com)

LiveScience.com

Do you have trouble getting a good night’s sleep? University of Wisconsin-Madison researchers are working on a gadget that can help you.

Dr. Giulio Tononi, professor of psychiatry at the UW-Madison School of Medicine and Public Health is working on a device that uses transcranial magnetic stimulation (TMS) to stimulate the slow brain waves characteristic of deep sleep.

TMS sends a harmless magnetic pulse through your skull to alter brain activity. In experiments, sleeping volunteers immediately began reproducing the slow, deep waves seen in Stage Three and Stage Four sleep.

Concerns Persist About RFID Tracking Technology

WISC-TV 3

MADISON, Wis. — Radio frequency identification, or RFID, is a new technology that might revolutionize the way businesses and even governments track objects.

And while experts say RFID holds tremendous positive benefits for both industry and consumers, questions remain about how invasive this technology could be for people.

RFID technology uses radio waves along with microchips and antennas called tags to give an object a unique number, similar to the idea of a Social Security number for items. Receiving devices called readers then remotely track the object from a distance and download information about it, WISC-TV reported.

Wall Street embraces TomoTherapy

Wisconsin State Journal

Investors warmly welcomed TomoTherapy’s entrance onto Wall Street on Wednesday.

Shares of the Madison medical equipment manufacturer opened at $24 on the Nasdaq market under the symbol TTPY. That was 26 percent higher than the initial public offering price of $19 a share, which was already up from the estimated $15 to $17 price range when the registration was filed in February.

Curiosities: Just like candy, continents melt in heat

Wisconsin State Journal

Q: If we think the continents were, at some point, all connected, how did they separate?

Abbie Stroup

Grade 7

Sennett Middle School

A: “The answer is rooted in the fact that our planet is a living’ planet, which is still cooling,” said Laurel Goodwin, professor of geology at UW-Madison. She describes the Earth as a series of shells, like a peanut M&M. “The candy shell is the crust, on which we live. The chocolate beneath is the mantle, and the peanut is the core — just imagine that the outer part of the peanut is molten.”

Deval Patrick: The promise of biotech (The Boston Globe)

Boston Globe

For decades Massachusetts has been fertile ground for the life sciences. Our unique concentration of extraordinary universities, teaching hospitals, research facilities, venture capital, and talent, spurred by a tradition of entrepreneurialism, provides a strong foundation for the growth in the biotech industry. These strengths have brought thousands of jobs and billions of dollars in life science investments to Massachusetts.

U.S. lab is good fit for Dane County

Wisconsin State Journal

Memo to the U.S. Department of Homeland Security:

As you consider where to build a $400-million federal laboratory to conduct research to fight animal and human diseases, you should be aware of the public support for putting the lab in Dane County.

Study Suggests Meditation Can Help Train Attention

New York Times

In meditation, people sit quietly and concentrate on their breath. As air swooshes in and out of their nostrils, they attend to each sensation. As unbidden thoughts flutter to mind, they let them go. Breathe. Let go. Breathe. Let go.

According to a study published today in the online edition of the journal PloS Biology, three months of rigorous training in this kind of meditation leads to a profound shift in how the brain allocates attention.

It appears that the ability to release thoughts that pop into mind frees the brain to attend to more rapidly changing things and events in the world at large, said the studyâ??s lead author, Richard Davidson, a professor of psychology and psychiatry at the University of Wisconsin in Madison. Expert meditators, he said, are better than other people at detecting such fast-changing stimuli, like emotional facial expressions.

Scientists test whether honey cures wounds

Wisconsin Public Radio

(UNDATED) Alternative medicine is not as widely used in the United States as it is in other parts of the world. But a vexing medical problem for diabetics is prompting a Wisconsin medical researcher to put an ancient remedy to the test.

Diabetics can get foot that donâ??t heal. This can lead to amputation. The best way to prevent this hasnâ??t been found; doctors have tried everything from gel therapy to maggots.

UW Health Assistant Professor of Family Medicine Jennifer Eddy works at a clinic in Eau Claire. She wants to try something different. She says thereâ??s a broad range of options and thatâ??s usually a sign in medicine that nothing has been clearly shown to be more effective than anything else. (Third item.)

UW’s Waisman lab explores the how and why behind an infant’s first words

Capital Times

A child’s first word is a special moment, their eyes widening in curiosity, one chubby finger pointing to an object in sudden recognition as “juice” or “train.” Forever written in baby books and memories, that first word is a triumph, their induction into the speaking world.

But it is what precedes that moment, the processes leading to language comprehension, that most interests the Waisman Center Infant Learning Lab.

“Our research provides us with a way to actually try to understand and study something that appears almost magical,” said Professor Jenny Saffran, who runs the Infant Learning Lab.

States vie to host deadly disease lab (AP)

A dozen states including Wisconsin are competing intensely to play host to a government lab full of killer germs like anthrax, avian flu and foot-and-mouth disease – a prospect some of their residents want to avoid like the plague.

Honey could save diabetics’ limbs: study (AFP)

Spreading honey on a diabetic ulcer could prevent the need to amputate an infected foot, researchers say.

A doctor at the University of Wisconsin who helped about half a dozen of her diabetic patients avoid amputation has launched a controlled trial to promote the widespread use of honey therapy.

The therapy involves squeezing a thick layer of honey onto the wound after dead skin and bacteria have been removed.