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Category: Research

Patent ruling isn’t a blow to UW’s research leadership

Milwaukee Journal Sentinel

Concern apparently has been voiced across the state that the recent U.S. Patent Office decisions rejecting three patents held by the patenting and licensing arm of the University of Wisconsin could be a devastating blow to the state’s acknowledged leadership in stem cell research.

As one of the parties who lodged the thus-far successful challenge against the overreaching patents on human embryonic stem cells held by the Wisconsin Alumni Research Foundation, let me reassure you that is simply not the case. And despite what WARF officials say, that’s not at all because appeals will be successful. A column by John Simpson.

Senate OKs stem cell funding bill

USA Today

In a largely symbolic act, the Senate voted Wednesday to lift restrictions on federal funding for embryonic stem cell research. President Bush has vowed to veto the measure, as he did last year, and backers acknowledged they don’t have the votes to override him. Still, proponents of the bill say they wanted to send the president a message: This issue isn’t going away.

Patent ruling isn’t a blow to UW’s research leadership

Milwaukee Journal Sentinel

Concern apparently has been voiced across the state that the recent U.S. Patent Office decisions rejecting three patents held by the patenting and licensing arm of the University of Wisconsin could be a devastating blow to the state’s acknowledged leadership in stem cell research.

As one of the parties who lodged the thus-far successful challenge against the overreaching patents on human embryonic stem cells held by the Wisconsin Alumni Research Foundation, let me reassure you that is simply not the case. And despite what WARF officials say, that’s not at all because appeals will be successful.

With Big Money Flowing to Biofuels Research, Universities Vie to Harvest Energy From Crops

Chronicle of Higher Education

On an overcast, chilly day in late March, scraggly rows of experimental crops line the test plots here at Iowa State University’s research farm.

Corn is king in Iowa, both as a food grain and now as a focus of efforts to rev up the biofuel industry. But these plants bear less-familiar names: switch grass, miscanthus, and kenaf.

The brown and black stalks are not much to look at, having weathered Iowa’s winter snows. But Iowa State researchers see these crops as seeds of change in alternative fuels. By summer, the grasses will be lush, tall, and green.

Round 2 on Stem Cells (Inside Higher Ed)

Inside Higher Education

After President Bush vetoed legislation that would have eased restrictions on federal funding for embryonic stem-cell research last year, supporters of the bill from both parties vowed to try again. That was even before the Democrats gained majorities in both houses of Congress.

Quoted: Terry Devitt, a spokesman at the University of Wisconsin at Madison.

Candidate expects challenge in top-20 goals (The University of Kentucky Kernel)

While the second candidate for Vice President for Research didn’t see UK’s top-20 goal as unrealistic, he said it might not be reached as soon as the university would like.

James Tracy, of the University of Wisconsin-Madison, said UK’s research goals for the Top 20 Business Plan’s 2020 deadline are a “steep climb.”

“I don’t know if you’ll get there,” Tracy said. “It might be 2020 or 2030.”

The Top 20 Business Plan isn’t unreasonable, he said, but it will be a challenge to implement.

Female chimps hunt with weapons

Daily Cardinal

Thousands of miles from Wisconsin, a Senegalese female climbed up a savannah tree and prepared herself for a hunt. Swiftly, she chose her weaponâ??transforming a nearby tree branch into a sturdy spear. With great force, she jabbed the wooden spear into the hollow spaces of the tree, hoping to immobilize potential prey. While the huntress failed to land many successful kills, her actions have captured the attention of scientists around the worldâ??the Senegalese huntress is not a woman, but rather one of our close cousins, the female chimpanzee.

Climate Change To Be Examined

Wisconsin State Journal

Climate change is on the agenda at UW-Madison this month.
Members of the state Senate Committee on Environment and Natural Resources will participate in a panel discussion on “Climate Change and Wisconsin’s Future: Issues and Opportunities” from 2:30 to 4 p.m. Tuesday in Room 180 of Science Hall, 550 N. Park St.

Second research candidate visits today (University of Kentucky Kernel)

Undergraduate research is exactly what UK needs, the second candidate to visit campus for the vice president of research position said Friday.

“Research changes the way we think about the world,” said Jim Tracy. “Undergraduates should be as involved as possible.”

Tracy, of the University of Wisconsin-Madison, is one of four candidates for the new vice president of research position. He will visit campus today and participate in a public forum from 4 to 5 p.m. on the 18th floor of the Patterson Office Tower.

Govâ??t rejects 3 stem cell patents

Daily Cardinal

The U.S. Patent and Trademark Office summarily rejected three of five stem cell patents last week that the Wisconsin Alumni Research Foundation has held since 1998, after two watchdog groups accused WARF of patenting â??elementaryâ? stem cell propagation techniques.

Stem cell bill has UW support

Capital Times

WASHINGTON — University of Wisconsin scientists are strongly backing a measure set for Senate debate next week that would override President Bush’s restrictions on stem cell research funding.

It would allow researchers to use embryos that would otherwise be discarded from fertility clinics.

“We feel that (the bill) will open up new avenues of this research,” said Andy Cohn, spokesman for the Wisconsin Alumni Research Foundation.

Doyle creates office to promote renewable fuel

Wisconsin State Journal

Gov. Jim Doyle continued to push his bioenergy policy Thursday as he launched initiatives to stimulate growth in the state’s renewable fuels industry while addressing the problems of global warming.

In front of a crowd that filled the UW-Madison Engineering Center atrium, the governor signed orders to create the Office of Energy Independence and the Task Force on Global Warming. Doyle also said the state will participate in the Midwest Renewable Energy Tracking System in cooperation with Minnesota, Iowa, South Dakota, North Dakota and the Canadian province of Manitoba.

UW-Madison Dedicates New Cereal Crops Lab

Wisconsin Ag Connection

The University of Wisconsin-Madison has officially dedicated its new Cereal Crops Research Unit. The facility, which will be operated by the USDA’s Agricultural Research Service, will serve as a testing venue for scientists to improve barley, oats and other cereal crops.

New Research Lab To Improve Inspections Of Barley, Oats

WISC-TV 3

MADISON, Wis. — A new research facility on the University of Wisconsin-Madison campus will improve inspections of barley and oats for foods and beverages that are shipped across the nation.

Researchers and politicians helped dedicate the $11 million USDA-ARS Cereal Crops Research Unit at 502 Walnut Street on Thursday morning.

They said that barley and oat inspections have been made in Madison for 75 years and that the new building will only continue that tradition.

Doyle creates office to promote renewable fuel

Wisconsin State Journal

Gov. Jim Doyle continued to push his bioenergy policy Thursday as he launched initiatives to stimulate growth in the state’s renewable fuels industry while addressing the problems of global warming.

In front of a crowd that filled the UW-Madison Engineering Center atrium, the governor signed orders to create the Office of Energy Independence and the Task Force on Global Warming. Doyle also said the state will participate in the Midwest Renewable Energy Tracking System in cooperation with Minnesota, Iowa, South Dakota, North Dakota and the Canadian province of Manitoba.

A passion for science: Three profiles of people devoted to research

Capital Times

Work as a scientific researcher means living a life that is full of questions, and being spurred by discoveries that reveal themselves in small increments.

The adventure is about knowing when to change directions, because the plotted route will be full of surprises and often in need of revisions. The reward is finding an answer to something that no one else knows, and being able to prove it, perhaps after years of experiments in uncharted territory.

Study finds flu’s drug resistance rising

Capital Times

Flu viruses with reduced sensitivity to drugs intended to prevent or limit infection have been found in patients not previously treated with these drugs, according to an international research team led by a UW-Madison researcher.

The emergence of drug-resistant influenza spreading by human-to-human contact was documented in a study of Japanese patients. University of Wisconsin virologist Yoshihiro Kawaoka was the lead author of a report on the findings in Wednesday’s Journal of the American Medical Association.

Doyle touts biofuels, renewables

Capital Times

Vowing the Midwest can become “the Saudi Arabia of renewable energy — with Wisconsin at the forefront,” Gov. Jim Doyle today unveiled the new Office of Energy Independence and gave support to a regional renewable energy credit trading system.

“If an oil field in Iran has to compete against a farm field in Wisconsin, that’s a very good thing for the environment, for our economy and for the world,” said Doyle in remarks prepared for an event today on the UW-Madison campus.

Editorial: Stem cells for all (Sacramento Bee)

In the mid-1990s, James A. Thomson of the University of Wisconsin helped launch the field of regenerative medicine by isolating embryonic stem cells and perfecting methods for self-perpetuating them in a laboratory.

Thomson’s work helped fuel the current push to study these cells, understand how they function and see if they can help cure spinal cord injuries, juvenile diabetes and other diseases. While Thomson deserves historic credit for his contributions, his university should not be allowed to own a patent on these cells, limiting how they can be used, by whom and at what cost.

Stemina hopes â??biomarkersâ?? blaze a profitable trail (wisbusiness.com)

www.wisbusiness.com

MADISON — Harnessing the power of stem cells in previously unexplored ways, Stemina Biomarker Discovery, Inc. is one of the newest startups to spring out of Madisonâ??s thriving biotechnology sector.

Elizabeth Donley, the companyâ??s chief executive officer, presented Steminaâ??s scientific goals and business model at the recent Molecular Medicine Tri-Conference in San Francisco.

Donley explained that when human embryonic stem cells are grown in culture, they can be used for disease diagnosis, screening drugs for side effects and reducing development costs of pharmaceuticals.

Bill Berry: State sets example with at-risk species

Capital Times

Aldo Leopold and his buddies would have enjoyed the moment. There I was, napping on a bench made of stone in the University of Wisconsin Arboretum when the pterodactyls approached. They surrounded me, but feigned disinterest and instead plucked last year’s crabapples from the Arboretum’s vast selection.

Was this a dream? No, it was turkeys, and how pleased the lovers of diversity who created the Arboretum would have been to see these giant birds enjoying a late afternoon fruit snack.

Is Wisconsin’s stem cell standing diminished?

Wisconsin Technology Network

Madison, Wis. – The legal wheels still have some spinning to do, but suddenly the prospect of the Wisconsin Alumni Research Foundation not owning three key stem cell patents, or deriving licensing income from them, seems very real.

The decision by United States Patent and Trademark Office examiners to reject WARF’s patent claims might still be overturned or modified, but for the first time since University of Wisconsin-Madison stem cell researcher James Thomson developed a method for isolating and defining human embryonic stem cells, some in Wisconsin are wondering whether the university actually has done something groundbreaking.

Study sees shifting Tamiflu resistance

Milwaukee Journal Sentinel

Tamiflu-resistant strains of flu have been found in patients who haven’t taken the drug, suggesting the mutated virus is capable of spreading between humans, according to an international team of researchers that includes a University of Wisconsin-Madison scientist.

Wisconsin governor backs state’s stem cell patents (Reuters)

Washington Post

Wisconsin Gov. Jim Doyle on Tuesday defended his state’s commitment to embryonic stem cell research after the U.S. patent office last week moved to revoke three
basic stem cell patents held by a Wisconsin foundation.

“As long as I am governor, the state will aggressively invest in, support and nurture this research,” Gov. Doyle said
in a statement.

Editorial: It’s patently obvious

Milwaukee Journal Sentinel

The Wisconsin Alumni Research Foundation, the licensing arm of the University of Wisconsin, has vowed to appeal the preliminary rejection of three of its key stem cell patents by the U.S. Patent and Trademark Office, even if the appeal process drags out in the courts for years.

This appeal should prevail, not for the sake of Wisconsin’s biotech industry and UW’s pioneering stem cell research efforts but on the abundant facts. This should occur soon to spare everyone involved the time, energy and expense of a protracted legal battle.

Geron opposes patent decision (San Francisco Examiner)

Menlo Park biotech company Geron Corp. (GERN) said Tuesday that it opposes a decision by the U.S. Patent and Trademark Office to reject a set of important embryonic stem-cell patents, to which it holds the commercial development rights.A company spokesman said the company was unlikely to be harmed by the ruling, however.

Through a patent licence with the Wisconsin Alumni Research Foundation, Geron holds the valuable commercial rights to develop treatments based on neural, cardio and insulin-producing cells developed from embryonic stem cells isolated by University of Wisconsin researcher James Thomson.

Study sees shifting Tamiflu resistance

Tamiflu-resistant strains of flu have been found in patients who haven’t taken the drug, suggesting the mutated virus is capable of spreading between humans, according to an international team of researchers that includes a University of Wisconsin-Madison scientist.
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Experts say the study, which showed anti-viral resistance in the milder influenza B viruses, means that Tamiflu-resistant strains of other flu viruses, such as the more fatal avian flu, could spread between humans, too.

Researchers find drug-resistance in less common strain of influenza in Japan (AP)

International Herald Tribune

CHICAGO: A less common strain of flu has shown hints of resistance to two flu drugs among patients in a small study in Japan, a country known for prescribing the drugs more frequently than anywhere else in the world.

Signs of resistance to the drugs Tamiflu and Relenza turned up among a few patients who had type B influenza, normally a milder flu causing smaller outbreaks than the more common type A.

UW can and must continue to lead

Wisconsin State Journal

UW-Madison suffered a setback Friday in its drawn-out and complicated battle to maintain three of its valuable stem-cell patents.

The U.S. Patent and Trademark Office indicated it is skeptical of the patents, which cover techniques for isolating embryonic stem cells.

But the case is hardly over.

U.S. invalidates three human stem cell patents (Los Angeles Times)

Los Angeles Times

The U.S. Patent and Trademark Office has invalidated three broad patents for human embryonic stem cells that have been blamed for slowing research in the highly visible field of regenerative medicine.The office ruled the discovery of embryonic stem cells from primates â?? including humans â?? was not worthy of patent protection because scientists had used similar methods to isolate embryonic stem cells from mice and other mammals, and described the cells’ potential for producing medical therapies.

3 Patents on Stem Cells Are Revoked in Initial Review

New York Times

The United States Patent and Trademark Office has made a preliminary decision to revoke three fundamental patents on human embryonic stem cells. If the decision stands, some scientists and consumer groups say it could loosen restrictions on research in a promising new field.

U.S. Rejects Wisconsin’s Patents on Stem-Cell Technology, but University Vows to Appeal

Chronicle of Higher Education

In a preliminary finding, the U.S. Patent and Trademark Office has determined that three broad patents issued to the University of Wisconsin at Madison on a technique for isolating and maintaining embryonic stem cells were issued in error because the technique wasn’t really new.

In rejecting the patents after re-examining them, the office found that the inventions described in them “would have been obvious to one skilled in the art” at the time the Wisconsin discoveries were made because of prior discoveries, which were known.

Games on the brain (Suburban Chicago Newspapers)

Do video games help kids learn?

If your immediate response to that question is, “Yeah, how to waste time and test your patience,” you’re probably the parent of a school-age child.

You might be surprised to learn that a panel discussion in Chicago recently saw educators and media specialists acknowledge that video games can not only teach, they just might be the springboard for a whole new approach to learning in the Information Age.

“We spend four, five, six years or more of a kid’s mathematical education teaching them what a 99-cent calculator can do,” said David Williamson Shaffer, an education professor at the University of Wisconsin-Madison and author of the new book How Computer Games Help Children Learn.

Stem-cell patents tossed

Milwaukee Journal Sentinel

The U.S. Patent and Trademark Office has issued a preliminary rejection of three key stem-cell patents owned by the University of Wisconsin-Madison, setting up a legal battle with potentially big economic and psychological ramifications for the state’s biotech economy.

The Wisconsin Alumni Research Foundation, the licensing arm of the university, vowed to appeal the ruling in every venue at its disposal, even if the dispute drags out in federal courts for years.

UW patents jeopardized

Wisconsin State Journal

The federal government has preliminarily rejected three controversial stem-cell patents held by UW-Madison, saying discoveries by researcher James Thomson were “obvious to one of ordinary skill.”

The decision could greatly affect the university’s prominence in the burgeoning field and stop the millions of dollars the patents are bringing in.

Critics of the patents, who say they stifle research, said the decision will likely kill the patents. But UW-Madison officials said they will appeal, a process that could take months or years. During that time, the patents will remain active.

Still: Wisconsin can offer what a federal energy research lab needs

Wisconsin Technology Network

Madison, Wis. – Researchers and engineers across Wisconsin are learning new ways to produce energy from cow manure, wood chips, organic sugars, soybeans, solar collectors, corn stover, wind farms, grease, waste from paper mills, and much more.

State businesses, architects, and builders are national leaders in planning and constructing â??greenâ? buildings that save energy and money.

Internet Story A Possible Factor

Wisconsin State Journal

A bizarre attack early Wednesday on a woman sleeping in her home turned stranger Friday when prosecutors said elements of the plot may have been taken from a sexual fantasy story found by the alleged attacker on the Internet.

States Take Lead in Funding Stem-Cell Research (NPR)

National Public Radio

State governments have taken the unusual step of funding biomedical research â?? usually done with federal grants â?? because of federal political decisions to restrict funding for embryonic stem-cell research.

Stem-cell scientists are naturally delighted by the new avenues of support, but there could be complications if scientists in different states want to collaborate.

Whether they deserve it or not, embryonic stem cells have come to represent potential salvation for many people suffering from incurable diseases.

Internet Use Can Boost Breast Cancer Patients’ Faith in Docs (HealthDay News)

Washington Post

Checking out high-quality breast cancer information online not only keeps patients informed about their disease, it may also boost their opinion about their doctor, new research shows.Previous studies have found that many breast cancer patients go online to learn more about their disease. This is the first study to look at how patients’ opinions about their doctors affect how they seek online information and support, and how the Web affects how patients regard their doctors, the study authors said.

UW Lab Worker Accused Of Chemical Attack On Student

WISC-TV 3

MADISON, Wis. — Prosecutors said a man accused of breaking into a college student’s apartment, pouring a chemical into the sleeping woman’s mouth and standing over her with a knife might have been following the plot of a sexual fantasy story from the Internet.

John Mulvihill, 56, was charged on Friday with armed burglary, first-degree reckless endangerment, second-degree reckless endangerment and resisting police after police said he attacked a UW-Madison student in her home with a chemical believed to be chloroform or ether.

Attack Suspect May Have Obtained Poison Through UW Labs

NBC-15

A Madison man accused of threatening and poisoning a woman with chemicals used to put animals to sleep may have committed more crimes like it.

Police say a UW student was attacked in her home on Mound Street earlier this week and her attacker may have stolen the chemicals to poison her with from UW’s Zoology Department. The suspect, John Mulvihill, appeared in court this afternoon and prosecutors say the crime he is accused of may not have been his first. The communities targeted could be anywhere from here to Minnesota.

The Sciences: Greening The World

CBSNews.com

Jonathan Foley, head of the University of Wisconsin’s Center for Sustainability and the Global Environment, or SAGE, cites the launch of Earth Day in 1970 as the original catalyst. But until recently, he says, “we’ve had an artificial separation” between the study of the natural environment and our human impact on it. Sustainability studies views the two as an inextricably connected whole. It addresses predicaments whose impact can be felt both locally (Greenland’s melting ice field, in one well-known example) and globally (the resulting potential for rising water levels and changing ocean currents).

Human Bodies Can Handle Only So Much Water

Wisconsin State Journal

Q. I saw on TV that a girl died from drinking too much water. How is that possible?
— Clarice Lightning grade eight Sennett Middle School

A. The human body is more than 50 percent water — it fills our cells, shuttles ions and nutrients, and clears out waste products. With so many crucial jobs, body fluid levels are very tightly regulated, says Dandan Sun, a UW-Madison professor of neurosurgery and physiology.

Lost world climates predicted

Milwaukee Journal Sentinel

A global warming study involving University of Wisconsin-Madison researchers says some climates of the world will be lost by 2100 and replaced by other climates not known in the world today.

Study Focuses On Prions

Wisconsin State Journal

Researchers at UW-Madison have found that prions, the malformed proteins that cause chronic wasting disease, move more easily through soils with high alkaline content.

UW-Madison researchers make fusion breakthrough

Wisconsin State Journal

Joe Talmadge recalls the moment when he and other UW- Madison engineers first fired up the magnetic plasma chamber, called a stellarator, they had built to study nuclear fusion.
The gathered scientists waited. And waited. Nothing happened.

UW study: Get ready for climates unknown

Capital Times

Known climates will disappear as a result of global warming, replaced by climates unknown in today’s world, a new study predicts. Entire plant and animal species could be lost as a result, said primary study author Jack Williams, a geographer at the University of Wisconsin-Madison.

Global climate models for the next century forecast the disappearance of climates currently found in tropical highlands and regions near the poles, according to the study by researchers at UW-Madison and the University of Wyoming.

100-Year Forecast: New Climate Zones Humans Have Never Seen

Scientific American

If global warming continues unabated, many of the world’s climate zones may disappear by 2100, leaving new ones in their place unlike any that exist today, according to a new study. Researchers compared existing patterns of temperature and precipitation with those that may exist at the turn of the century, based on scenarios put forth in the recent report of the Intergovernmental Panel on Climate Change (IPCC). They found that if greenhouse gas emissions continue rising at the same rate, up to 39 percent of Earth’s continental surface may experience totally new climates, primarily in the tropics and adjacent latitudes as warmer temperatures spread toward the poles.

Doubts cloud adult stem cell research

USA Today

A magazine investigation has raised new doubts about pioneering adult stem cell studies, leaving questions about the much-touted medical potential of these cells. A report in New Scientist magazine finds “apparently duplicated (images) being used to describe results from different experiments” in a 2006 patent obtained by University of Minnesota researchers.