In an accompanying editorial, Kristen Malecki, Ph.D., MPH, of the University of Wisconsin-Madison, noted that the findings support the importance of research examining interactions between epigenetics and low-cost therapies such as aspirin. According to Dr. Malecki, “The study by Wang et al. shows that beyond gene-environment interactions, epigenetic and environment interactions also exist, and suggest that DNA methylation could in the future help to support the identification of individuals for whom treatment may or may not be successful.
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