While there’s a “much larger body of evidence” suggesting beneficial metabolic effects of akkermansia, the studies pointing to potential downsides should not be ignored, said Federico Rey, a microbiologist at the University of Wisconsin at Madison who studies the relationship between the gut microbiome and cardiometabolic disease. “The overwhelming data suggests that akkermansia is good for your metabolic health, but there’s also data suggesting that it might not be good for other conditions,” he added. “There’s a lot of moving parts we still have to understand before making general recommendations.”