Noted: The momentum has been building since April 2005, when Nimmerjahn published his movies2. A month later, a team led by Wen-Biao Gan ? a neuroscientist at New York University, who first developed the skull-thinning method ? published similar results6. ?This was a major breakthrough and inspired a lot of people,? says Marie-Ève Tremblay, a postdoctoral researcher at the University of Wisconsin?Madison who studies the role of microglia in sleep and wakefulness.