Yoshihiro Kawaoka put into words a question that worries many scientists watching this situation, the worry that underscored Fouchier’s insistence that this outbreak must be stopped as quickly as possible. “We do not know whether the bovine H5N1 virus will become established in cattle,” wrote Kawaoka, a flu virologist at the University of Wisconsin-Madison. “If it does, will it evolve to adapt more towards ‘mammalian-like’ influenza viruses? … Will it pose a risk to human health?”