Everything you need to know about the ‘age-reversal’ supplement NAD+

According to Guarente, pellagra is characterized by what are known as the four Ds; dermatitis, diarrhea, dementia, and death. “Pellagra turned out to be a disease of NAD+ deficiency and the molecules that could prevent and/or cure it were termed vitamin B3s,” he says, which Conrad Elvehjem, a professor at the University of Wisconsin-Madison, proved in 1937.