What do you do when you?ve had a bad day? Depending on the depths of the badness, the cash and time at your disposal, and your post-trauma ability to make complete sentences, you can curl up with a book, hit the gym or the fridge, shop, watch YouTube, or call your mom.
Category: Research
An Engineered Doomsday
Scientists have long worried that an influenza virus that has ravaged poultry and wild birds in Asia might evolve to pose a threat to humans. Now scientists financed by the National Institutes of Health have shown in a laboratory how that could happen. In the process they created a virus that could kill tens or hundreds of millions of people if it escaped confinement or was stolen by terrorists.
Ritalin’s brain target pinpointed by UW researchers
The drug Ritalin has been used for years to help people with attention deficit hyperactivity disorder (ADHD). But it wasn?t until now that researchers at UW-Madison have discovered where in the brain the drug works. Psychology professor Craig Berridge and graduate student Robert Spencer have identified the upper portion of the brain?s prefrontal cortex as the key area where Ritalin works.
Renowned evolutionary biologist and popular professor James Crow dies at 95
James F. Crow, one of the world?s most eminent evolutionary biologists and a popular UW-Madison professor for more than 40 years, died Wednesday in Madison. He was 95. The university named its Institute for the Study of Evolution after Crow in 2009.
“Jim was a major figure in the history ? up to the present ? of evolutionary genetics,” said John Hawks, an associate professor of anthropology. In addition to his research on the behavior of genes and the effects of radiation on the human mutation rate, Crow served on a number of groundbreaking national committees. He chaired a national committee that compiled a report on the use of DNA evidence in the courtroom.
UW superheating project aims to explore magnetic fields
Researchers will be able to simulate the superheated gases that form the suns magnetic field with a one-of-a-kind sphere that moved Wednesday into a new physics lab at the University of Wisconsin-Madison.
Science and Security Clash on Bird-Flu Papers
It was the week before Christmas, and D.A. Henderson was alarmed about germs. He isn?t easily rattled: Dr. Henderson led the successful worldwide effort to eradicate smallpox in the 1970s, and he directed the U.S. Office of Public Health Emergency Preparedness after the deadly anthrax letter attacks and the destruction of the World Trade Center in 2001. But recently not just one but two laboratories had engineered the virus known as bird flu to make it easily transmissible?through the air, among mammals?and that was a scary development. “Compared to plague or to anthrax, this one has a potential for disaster that dwarfs all others,” says Dr. Henderson, now a distinguished scholar at the Center for Biosecurity of the University of Pittsburgh Medical Center. “Given our flu-vaccine capacity, which is limited, this could be a catastrophe if it gets out.” The experiments shouldn?t have been done, in his view, and?partly because they could give terrorists a blueprint for making a more deadly form of H5N1 avian-influenza virus?they certainly shouldn?t be published.
UW-Madison virologist Yoshihiro Kawaoka and Ron Fouchier, a virologist at the Erasmus Medical Center in the Netherlands, are mentioned in this article.
Editorial: On Wisconsin
In a few hours it?ll be all about the football. But it?s been interesting these last several days to hear University of Wisconsin administrators and fans talk about the image boost UW gets from playing in the Rose Bowl. If you haven?t seen the new UW promotional ad, you?ll see it during the game, but it highlights some of the discoveries and research that originated at UW and it?s impressive.
Emmett L. Bennett Jr. Dies at 93, Expert on Ancient Script, Dies at 93 (NYTimes.com)
Emmett L. Bennett Jr., a classicist who played a vital role in deciphering Linear B, the Bronze Age Aegean script that defied solution for more than 50 years after it was unearthed on clay tablets in 1900, died on Dec. 15 in Madison, Wis. He was 93. His daughter Cynthia Bennett confirmed the death.
Professor Bennett was considered the father of Mycenaean epigraphy ? that is, the intricate art of reading inscriptions from the Mycenaean period, as the slice of the Greek Bronze Age from about 1600 to 1200 B.C. is known. His work, which entailed analysis so minute that he could eventually distinguish the handwritings of many different Bronze Age scribes, helped open a window onto the Mycenaean world.
2011 was a year for thinking big
Mentions former Chancellor Biddy Martin’s push for public authority status for UW-Madison, as well as several UW-Madison research advances.
Editorial: Flu debate focuses on wrong question
The bird flu censorship debate, while far too narrowly focused, is nonetheless a timely reminder of how badly we need to stay on guard against a pathogen too often dismissed as the flu bug.
Bowl ad deftly boosts UW-Madison to nation
A sophisticated new ad about the University of Wisconsin-Madison to air during the Rose Bowl telecast is a cutting-edge effort, featuring UW?s development of disease-resistant crops, the first micro motor and research in Antarctica.
Ask the Weather Guys: What were the top Wisconsin weather events for 2011?
Each season in 2011 had a memorable weather event, some with negative impacts. There were two good snow storms in February. The Groundhog Day blizzard had wind gusts of up to 60 mph and snowfall depths ranging from 1 to 2 feet. That resulted in snow drifts of 6 to 10 feet. The second storm occurred on February 20-21 with snow accumulations between 8 and 15 inches. Freezing rain and sleet also fell across southern Wisconsin.
….During the year, 10 people were directly killed by weather events: one person from a blizzard, one from lightning, one from a tornado, one from non-tornadic thunderstorm winds, one from flooding and five during the July heat wave.
Curiosities: Why does plastic dry slower than glass?
A. Ever wonder why Tupperware containers retain huge droplets of water after a dishwasher cycle, or why plastic cups take longer to air-dry than their glass counterparts? UW-Madison physics Professor Clint Sprott explains that two factors are at play: cohesion and adhesion.
Anthony S. Fauci, Gary J. Nabel and Francis S. Collins: Dangerous flu virus research a risk worth taking
A deadly influenza virus has circulated widely in birds in recent years, decimating flocks but rarely spreading to humans. Nonetheless, because of its persistence in bird flocks, this highly pathogenic virus has loomed as a major public health threat. Seasonal influenza kills less than 1 percent of the people it infects. In contrast, human infections with the H5N1 virus, though exceedingly rare, are fatal in most cases. Should this virus mutate in a way that allows it to be transmitted as efficiently among people as seasonal influenza viruses are, it could take an unprecedented toll on human life.
A number of important scientific and public health questions regarding this virus remain unanswered, including the likelihood of such mutations arising and the mechanisms by which they may occur. Two recent studies co-funded by the National Institutes of Health (including research conducted by UW-Madison bird flu expert Yoshihiro Kawaoka) have shed light on how this potentially grave human health threat could become a reality.
An Explanation of How Avian Flu Spreads
Recent reports that two teams of scientists had genetically altered a deadly flu virus to make it more contagious have provoked fear, even outrage, in some quarters.
How to Research Deadly Germs Without Helping Terrorists
Bird flu kills more than half the people who catch it. The saving grace of H5N1 is that it?s not easily spread among humans. Almost all of the 600 people who have been infected by the virus in its 14-year history have picked it up from infected poultry.
Patients donate locally to support medical research for personal connections
When Greg Szymanski started raising money for eye research, he decided not to give it to a foundation far away. He donated the money to the lab of Dr. David Gamm, a UW-Madison retina specialist using stem cells to better understand and treat vision loss. “I wanted to help right here, where we have specialists who work on these diseases,” said Szymanski, 62, of Madison, who lost most of his sight seven years ago. Unlike government grants that pay for most medical research, Szymanski?s money comes with few restrictions, Gamm said.
Citizen Dave: We might have been a part of it, New York, New York
Imagine if the University of Wisconsin had a campus in New York City dedicated to competing with MIT and Stanford for being the premiere science and high tech research campus in the nation. That possibility was on the table recently when Mayor Michael Bloomberg announced a competition to create a new world-class science campus on underutilized acreage on Roosevelt Island in the East River. The land for the new campus would be given free to the university that competed successfully for it. Bloomberg was offering a $400 million grant in land and infrastructure.
Too late to contain killer flu science, say experts (The Independent)
Attempts to censor details of controversial influenza experiments that created a highly infectious form of bird-flu virus are unlikely to stop the information from leaking out, according to scientists familiar with the research.
Scientists? bird flu study almost puts millions at risk (New York Daily News)
America has no Galileos. Here, we proudly defend the freedom of scientists to go wherever the evidence takes them.
Controversial research on bird flu (Los Angeles Times)
LOS ANGELES — In a top-security lab in the Netherlands, scientists guard specimens of a super-killer influenza that slays half of those it infects and spreads easily from victim to victim.
Medtronic paid millions to influential UW chairman
Paul Anderson, an orthopedic surgeon at the University of Wisconsin-Madison, gets so much money from the medical device firm Medtronic that the university put its most stringent oversight on the relationship.
One of the requirements is that Anderson, who has received $225,000 in consulting fees from Medtronic in 2008 through 2010, has to meet annually with his department chairman to review the relationship and its potential influence on his university activities.
But the chairman, Thomas Zdeblick, got more than 25 times that amount from Medtronic himself during the three years. And a new accounting by the Journal Sentinel and MedPage Today shows he received more than $25 million in royalties from the company since 2003.
Science and Censorship: A Duel Lasting Centuries
The specter of censorship loomed over science last week with news that a federal advisory panel had asked two leading journals to withhold details of experiments out of fear that terrorists could use the information to make deadly flu viruses ? the first time the government had interceded this way in biomedical research.
H5N1: the lab-made virus the U.S. fears could be made into a biological weapon
Two teams of researchers, one in the Netherlands and one at the University of Wisconsin, have run experiments to find mutations that can turn H5N1 from a bird flu to a mammal flu. They?ve carried out their experiments on ferrets, which respond to flu viruses much like humans do.
The Trouble with Scientific Secrets (The New Yorker)
Instead of focusing so heavily on human terrorists, we ought to take this opportunity to defeat a natural pathogen?one we can now recognize and manipulate with all the sophistication of molecular biology.
Security in H5N1 Bird Flu Study Was Paramount, Scientist Says
The National Science Advisory Board for Biosecurity, concerned about bioterrorism and a worldwide pandemic, has for the first time ever urged scientific journals to keep details out of reports that they intend to publish on a highly transmissible form of the bird flu called A(H5N1), which has a high death rate in people.
Concerns over terrorist potential with UW research
Officials with the National Institutes for Health are recommending restrictions on the publishing of the findings of a UW-Madison?s researcher?s work on avian flu, over fears bioterrorists could use the information.
A Conversation With Jack Williams (The Atlantic)
In his research, Jack Williams, director of the Nelson Institute Center for Climatic Research, studies the impact climate change had at the end of the last ice age–around 15,000 years ago–when global temperatures rose by 9°F.
By analyzing ancient materials trapped in lake beds, he and his colleagues in the field have come to some startling conclusions. For one, small fluctuations in global temperature can cause large-scale biological changes across the planet, including mass migrations and extinctions.
A Conversation With Jack Williams, Director of the Nelson Institute Center for Climatic Research (The Atlantic)
As climate change continues to tick the Earths temperature upward, we can learn what to expect of a hotter planet by looking at the past. In his research, Jack Williams, director of the Nelson Institute Center for Climatic Research, studies the impact climate change had at the end of the last ice age–around 15,000 years ago–when global temperatures rose by 9°F. By analyzing ancient materials trapped in lake beds, he and his colleagues in the field have come to some startling conclusions. For one, small fluctuations in global temperature can cause large-scale biological changes across the planet, including mass migrations and extinctions.
Campus Connection: Feds ask that bird flu study conducted at UW-Madison be censored
A committee that advises the federal government on biosecurity issues is recommending that the details of two experiments on the H5N1 avian influenza virus — including research conducted by UW-Madison bird flu expert Yoshihiro Kawaoka — not be made public due to fears that terrorists could use the information to create a bioweapon.
Feds asked researchers at UW to withhold details about bird flu creation
WASHINGTON ? The U.S. government asked scientists at two research centers, including UW-Madison, not to reveal all the details of how to make a version of the deadly bird flu that they created in labs in the U.S. and Europe. Bill Mellon, UW-Madison associate dean for research policy, said virology professor Yoshihiro Kawaoka has gone through several iterations of a manuscript to the journal Nature to comply with the recommendations.
“That is an awkward situation to be in because, obviously, we?re interested in disseminating science,” Mellon said.
Federal panel asks journals to censor reports of lab-created ?bird flu?
Scientists seeking to fight future pandemics have created a variety of ?bird flu? potentially so dangerous that a federal advisory panel has for the first time asked two science journals to hold back on publishing details of research.
Research on Lethal Bird Flu May Be Censored on Concern at Terrorism Risk
Scientists agreed not to publish certain details of research showing how lethal bird flu can be made contagious after a U.S. biosecurity panel asked that it be kept secret for security reasons.
Armageddon virus: call to keep H5N1 bird flu killer recipe secret
Two top scientific journals say they are deciding whether to publish details of a man-made mutant flu virus that could kill billions, after a US government?s science advisory committee advised them to withhold key details.
Fears grow over lab-bred flu
It is a nightmare scenario: a human pandemic caused by the accidental release of a man-made form of the lethal avian influenza virus H5N1.
U.S. Says Details Of Flu Experiments Should Stay Secret
A committee that advises the government says that details of two controversial experiments on bird flu virus should not be made public, because of fears that the work could provide a recipe for a bioweapon.
Bird flu terrorism fear over study?s publication (Toronto Star)
A U.S. scientific advisory board has asked two scientific journals ? Nature and Science ? to publish redacted versions of two controversial studies on bird flu virus because of fears of bioterrorism.
Bird flu: Research row as US raises terror fears
US authorities have asked the authors of two controversial bird flu studies to redact key details after a government advisory panel suggested the data could be used by terrorists.
Details of lab-made bird flu won’t be revealed
The U.S. government paid scientists to figure out how the deadly bird flu virus might mutate to become a bigger threat to people ? and two labs succeeded in creating new strains that are easier to spread.
U.S. Asks Journals to Censor Articles on Bird Flu Virus
For the first time ever, a government advisory board is asking scientific journals not to publish details of certain biomedical experiments, for fear that the information could be used by terrorists to create deadly viruses and touch off epidemics.
Brown Christmas likely for south-central Wisconsin
Based on the best and latest weather science, it appears that you will look out your window on Christmas morning and see mostly brown grass. Maybe. Jonathan Martin, professor and chairman of the Department of Atmospheric and Oceanic Sciences at the UW-Madison, said that everything from satellite data to computer models to numerical weather forecasts are telling us that, though snowless Christmases are rarer than skinny mall Santa Clauses, this coming holiday may indeed buck the trend.
Erika Cardenas: Leave the fish that help keep lakes clean
Fish responsibly this season. The fishes are of questionable nutritional value anyway, so just catch and release to keep our best in-lake eutrophication control strong.
? Erika Cardenas, student, UW-Madison
UW scientists under scrutiny over bird flu research (WTMJ-TV, Milwaukee)
Starting with the virus that causes bird flu, two scientists have created a highly contagious version in the laboratory that one calls “probably one of the most dangerous viruses you can make.”
Ask the Weather Guys: When is the winter solstice?
The winter solstice (from the Latin sol, or “sun,” and stice, or “come to a stop”) is the day of the year with the fewest hours of daylight. This year, this occurs for the Northern Hemisphere at 11:30 pm Wednesday.
UW bird flu research seen as bioterror threat
A University of Wisconsin-Madison scientist who is an expert on the avian flu virus is under scrutiny because of concerns his new research may fall into the wrong hands.
The scientist is Yoshihiro Kawaoka, an eminent professor of virology in the School of Veterinary Medicine who has done research on H5N1, also known as the avian bird flu. His work and similar research independently done by a Dutch scientist have raised concerns in science journals and on an NBC News report that aired Thursday night that touched on such controversial issues as bioterrorism and scientific freedom.
UW contingent commemorates 1911 trek to South Pole
Some two dozen people with ties to the University of Wisconsin-Madison joined the prime minister of Norway and a contingent of scientists and explorers at the bottom of the earth on Wednesday to commemorate the 100th anniversary of Norwegian Roald Amundsen becoming the first person to reach the South Pole.
The Bioterrorist Next Door (Foreign Policy)
In September, an amiable Dutchman stepped up to the podium at a scientific meeting convened on the island of Malta and announced that he had created a form of influenza that could well be the deadliest contagious disease humanity has ever faced. The bombshell announcement, by virologist Ron Fouchier of Erasmus Medical Center, sparked weeks of vigorous debate among the world?s experts on bioterrorism, influenza, virology, and national security over whether the research should have been performed or announced and whether it should ever be published.
Dr. Zorba Paster: Addicted to nicotine gum? At worst, it’s still better than smoking
PPS: Great tips for stopping smoking and more are on UW-Madison?s world famous Center for Tobacco Research and Intervention website at www.ctri.wisc.edu. They are pioneers in helping you stop.
CDI announces launch of neuron product
Cellular Dynamics International is out with a new product: stem cell-derived neurons. The Madison company, founded by UW-Madison stem cell pioneer James Thomson, says it is the first commercial release of human brain cells, created through the company?s stem cell technology, in large enough quantity, quality and purity for use in life science research.
Ann Brenoff: Girls Are Good At Math, New Study Claims
Back in 2005, then-Harvard president Lawrence Summers proclaimed that boys were simply better at math because, well, because they were boys. It was a statement once-removed from sending the little ladies back into the kitchen with aprons tied around their waists and frankly, the backlash that quickly followed and pulverized Summers was well-deserved.
Skin sample is two million years old? (Pravda)
Many believe that fossils represent organisms that died millions of years ago. Scientific literature, however, contains dozens of well-described original soft tissues in fossils. Since laboratory tests have shown that organic tissues decay in only thousands of years, these fossils have been at the center of much heated controversy.
Hawks: Occupy Federal Science: ?Transformative? Research Can?t Come From Milquetoast
Philip Ball writes in The Guardian about another new initiative from NSF to fund ?potentially transformative? research. He begins his essay with this…
‘Gender math gap’ is cultural, not biological
Many explanations for the gender gap in math skills don?t hold up, suggests new research on math skills and gender in 86 countries.
Girls are no worse than boys at maths: Study in 86 countries shows differences caused by attitudes to women
Scientists have previously believed that the relatively low numbers of women in high-level mathematics could be due to biological differences between men and women. But a new, international study at the University of Wisconsin-Madison has cast doubt on the idea that the differences are biological at all.
UW researcher honored in D.C.
A UW researcher was honored at the White House Friday for her work to provide more opportunities for women and underrepresented minorities in the fields of science, technology, engineering and mathematics.
Research at South Pole marks 100 years
The University of Wisconsin?s IceCube Research Center will be hosting celebrations in honor of the 100th anniversary of the first-ever trek to the South Pole this upcoming Tuesday.
Making viruses the natural way
Discover’s Carl Zimmer on cutting-edge flu research and the way it’s portrayed by news media.
Ask the Weather Guys: Why does the moon look red during a lunar eclipse?
A: A total lunar eclipse could be seen in cloud-free regions across most of the United States and Canada on Saturday morning, Dec. 10. In a total lunar eclipse the sun, Earth and moon line up and the Earth casts its shadow on the moon. The moon is always a full moon and it never goes completely dark during a total lunar eclipse. It appears reddish for the same reason that sunsets and sunrises often have a red tint.
Curiosities: Why do kids laugh more than adults?
A: It?s not clear that they do, says Robert McGrath, coordinator of mind/body wellness services at University Health Services at UW-Madison. McGrath has seen a study that found that children laugh no more than adults, but added that kids do have some advantages in the laughter department.
Not everyone gives an ‘A’ to single-gender classrooms
Marshall Middle School is into its fifth year of an experiment in single-sex education, a practice under attack from some who say it doesn?t work and could harm students. Janet Hyde, an authority on the role of gender in education at UW-Madison calls single-sex education theory “pseudoscience.”