Skip to main content

Category: Research

New kind of stem cells can turn into heart cells, University of Wisconsin-Madison researchers show

Wisconsin State Journal

A new kind of stem cells developed by UW-Madison researcher James Thomson performs like his old kind in a lively way.

The new cells can be turned into heart cells that beat in a lab dish, other scientists on campus have shown. The achievement could lead to a better understanding of heart disease and therapies crafted from the skin of patients with heart problems.

University of Wisconsin-Madison prof elected to engineering academy

Capital Times

University of Wisconsin-Madison Professor Guri Sohi was elected to the National Academy of Engineering.

Sohi is among 65 engineers and nine foreign associates elected in 2009. Those named to the academy were peer-elected for their exceptional contributions to engineering research, practice or education.

First head of University Research Park dies at 79

Capital Times

Wayne McGown, a man who held top positions under six state governors and four University of Wisconsin-Madison chancellors before being chosen as the first director of the University Research Park, passed away Tuesday after a battle with cancer. He was 79.

The only child of Homer and Amy McGown, Wayne grew up in Stevens Point and went on to graduate from UW-Madison with a bachelor’s in accounting and a master’s in political science.

Nothing to sneeze at decoding the common cold

USA Today

Scientists have unraveled the genetic code of the common cold â?? all 99 known strains of it, to be exact. In fact, the genetic blueprints showed that you can catch two separate strains of cold at the same time â?? and those strains then can swap their genetic material inside your body to make a whole new strain.

It’s why we’ll never have a vaccine for the common cold, said biochemist Ann Palmenberg of the University of Wisconsin-Madison College of Agricultural and Life Sciences, who led the three teams that assembled the family tree of the world’s rhinoviruses.

New Biomarker For Fatal Prostate Cancer

Scientist Live

New research findings out of Wake Forest University School of Medicine and the University of Wisconsin may help provide some direction for men diagnosed with prostate cancer about whether their cancer is likely to be life-threatening.

Expert Says Antibiotics Can Pose Health Risks In Food

WISC-TV 3

As the agriculture industry is in the spotlight following cases of salmonella, a local expert is sharing his thoughts on ways to make food safe for consumers.

Feeding millions of people around the world starts with feeding animals. While some farmers use antibiotics to help grow livestock, a local expert said he believes it carries risk.

“The micro-organisms that are in the gut of these animals become resistant, and when people get infected with these organisms, they’re getting resistant organisms. They’re getting infections, (and are) infected with organisms that are multi-drug resistant,” said Dr. Dennis Maki, an expert on infectious diseases at the University of Wisconsin-Madison School of Medicine.

Cure for the Common Cold? Not Yet, but Possible

New York Times

Curing the common cold, one of medicineâ??s most elusive goals, may now be in the realm of the possible.

Researchers said Thursday that they had decoded the genomes of the 99 strains of common cold virus and developed a catalog of its vulnerabilities.

Scientists are inching closer to a cure for the common cold

Chicago Tribune

Scientists announced Thursday that they have cracked the genetic code of all known species of the common cold virus, a major step forward in the effort to develop a cureâ??and perhaps even a vaccineâ??or the common cold.

The findings, published this week in the journal Science, highlighted why researchers have found it so difficult to build effective drugs to combat the virus, which sickens millions each year and sends thousands of children with asthma to the hospital.

Nothing to sneeze at — decoding the common cold (AP)

Chicago Sun Times

Scientists have unraveled the genetic code of the common cold — all 99 known strains of it, to be exact.

But don’t expect the feat to lead to a cure for the sniffling any time soon. It turns out that rhinoviruses are even more complicated than researchers originally thought.

In fact, the genetic blueprints showed that you can catch two separate strains of cold at the same time — and those strains then can swap their genetic material inside your body to make a whole new strain.

Scientists crack cold viruses’ genetic code (CanWest News Service)

Scientists are boldly predicting we may soon have to stop complaining that if we can put a man on the moon, why can’t we cure the common cold?

Researchers have cracked the genetic code for all 99 known strains of the human rhinovirus, the virus that accounts for the majority of human cold infections.

The work, published this week in the journal Science, could lead to the first effective treatments for the common cold within five years, researchers say.

Skin Cells Turned Into Working Heart Muscle (HealthDay News)

Forbes

It may be possible to use skin cells to create stem cells that can repair damaged hearts, researchers at the University of Wisconsin-Madison report.

In late 2007, UW-Madison researchers showed that skin cells could be turned back into stem cells. In this new study, these induced pluripotent stem (iPS) cells were used to create working heart-muscle cells (cardiomyocytes).

Chancellor urges humanities scholars to be in touch with public

Wisconsin State Journal

Humanities scholars at the University of Wisconsin-Madison could do a better job of communicating their value to the public, Chancellor Biddy Martin said at a lecture Wednesday.

Speaking on the topic of “humanities in the public,” Martin explored the challenges of translating academic research in subjects like English, history and philosophy to broad audiences.

Adventures in evolution

MSNBC.com

Evolutionary biology isn’t just something you do in the lab or the library: Over the past two centuries, scientific pioneers have had to weather seasickness, survive shipwrecks and watch out for polar bears while they ferreted out the facts.

In his latest book, “Remarkable Creatures,” molecular biologist Sean B. Carroll recounts the rip-roaring adventure tales behind the great advances in the theory of evolution.

Empathy Might Be in the Genes

U.S. News and World Report

Genes may play a role in a person’s ability to empathize with others, suggests a U.S. study involving mice.

Researchers trained highly social mice to identify a sound played in a specific cage as negative by also having squeaks of distress come from a mouse in that cage. But a genetically different strain of mice that were less social didn’t make the same negative connection.

Turning Biomass Into Biofuel

Scientist Live

Taking a chemical approach, researchers at the University of Wisconsin-Madison have developed a two-step method to convert the cellulose in raw biomass into a promising biofuel. The process, which is described in the Wednesday, Feb. 11 issue of the Journal of the American Chemical Society, is unprecedented in its use of untreated, inedible biomass as the starting material.

The key to the new process is the first step, in which cellulose is converted into the “platform” chemical 5-hydroxymethylfurfural (HMF), from which a variety of valuable commodity chemicals can be made. “Other groups have demonstrated some of the individual steps involved in converting biomass to HMF, starting with glucose or fructose,” says Ronald Raines, a professor with appointments in the Department of Biochemistry and the Department of Chemistry. “What we did was show how to do the whole process in one step, starting with biomass itself.”

They Don’t Make Homo Sapiens Like They Used To

Discover Magazine

Bones donâ??t lie. John Hawks of the University of Wisconsin at Madison likes evidence he can put his hands on, so he takes me on a tour of the universityâ??s bone laboratory. There, the energetic 36-year-old anthropologist unlocks a glass case and begins arranging human skulls and other skeletal artifactsâ??some genuine fossils, others high-quality reproductionsâ??on a counter according to their age. Gesturing toward these relics, which span the past 35,000 years, Hawks says, â??You donâ??t have to look hard to see that teeth are getting smaller, skull size is shrinking, stature is getting smaller.â?

UW Reactor To Ditch Highly Enriched Uranium

WISC-TV 3

A nuclear reactor at the University of Wisconsin-Madison will be converted to run on less dangerous fuel under a national safety initiative.

UW-Madison officials said the reactor’s fuel will be converted from highly enriched uranium to low enriched uranium this year or early next year. The school said leftover fuel will be stored at a lab in Idaho.

UW Reactor To Ditch Highly Enriched Uranium

WISC-TV 3

MADISON, Wis. — A nuclear reactor at the University of Wisconsin-Madison will be converted to run on less dangerous fuel under a national safety initiative.

UW-Madison officials said the reactor’s fuel will be converted from highly enriched uranium to low enriched uranium this year or early next year. The school said leftover fuel will be stored at a lab in Idaho.

T

Darwin still raising controversy…for another reason

Capital Times

Charles Darwin was able to stir up almost as much controversy with notions about dogs and emotions as with chimps and evolution.

The British naturalist, born 200 years ago on Feb. 12, transformed how the scientific community thinks about the evolution of plant, animal and human life through his brilliant, seminal work, “On The Origin of Species.”

Although Darwin’s pioneering notions about natural selection and evolutionary biology continue to draw plenty of fire and fury from religious creationists, he has another book that ruffles feathers, too.

The evolution of Darwin’s theory

Los Angeles Times

Blue eyes are typically associated with beauty, or perhaps Frank Sinatra. But to University of Wisconsin anthropologist John Hawks, they represent an evolutionary mystery.

For nearly all of human history, everyone in the world had brown eyes. Then, between 6,000 and 10,000 years ago, the first blue-eyed baby was born somewhere near the Black Sea.

UW acts to eliminate roadblocks

Milwaukee Journal Sentinel

An innovation hothouse like Madison’s University Research Park will be a part of every school in the UW System if a new Board of Regents task force meets its expectations.

Aiming for sweeping change, UW System President Kevin Reilly said Friday he’s pulling together a high-profile group to uncover roadblocks that need to be removed and incentives that need to be put into place to move more university research into the hands of Wisconsin businesses and start-up companies.

UW celebrates Charles Darwin

WKOW-TV 27

His theory of evolution is accepted in many circles, controversial in others.

Regardless, Saturday was Darwin Day at UW-Madison. It was the fourth year in a row the event took place close to the birthday of evolution expert Charles Darwin. He was born 200 years ago on February 12.

The day long festivities included biology and evolution experts as guest speakers, as well as a look at evolution research going on at the campus.

Darwin will be the big man on campus Saturday at the University of Wisconsin-Madison

Wisconsin State Journal

To Tony Goldberg, a professor in the University of Wisconsin-Madison’s School of Veterinary Medicine, the concept of evolution is far from a dusty theory. It’s a real process that informs just about everything he does in his laboratory.

Goldberg studies the ecology and evolution of disease and disease-causing organisms and he sees evolution every time he studies a virus or a bacteria that has changed to resist our latest efforts to control it.

Curiosities: When does a recession become a depression?

Wisconsin State Journal

Q: Whatâ??s the difference between an economic recession and a depression?

A: The “official” arbiter of recessions is the National Bureau of Economic Research (NBER), a private, nonprofit research organization, comprised of a number of top economists, according to Stephen Malpezzi, Lorin and Marjorie Tiefenthaler Professor of Real Estate and Urban Land Economics at the Wisconsin School of Business.

Evolutionary biologist Sean Carroll honors Darwin, other naturalists

Capital Times

Charles Darwin, Alfred Russel Wallace and Henry Walter Bates were all under 25 when, more than 150 years ago, they set out from England to explore the wild and virtually unknown jungles of South America.

While Darwin embarked on his famous voyage in 1831 on the navy vessel the HMS Beagle, Wallace and Bates explored the Amazon two decades later on commercial trading ships. These three naturalists not only proposed and developed the idea of natural selection, but helped provide the evidence to support their beliefs and solve “the problem of the origin of species.”

Psychologist looks to monks for keys to happiness

Salt Lake Tribune, The

Evolution has given the human brain a vast prefrontal cortex, a ball of neural tissue that enables us to engage in abstract reasoning, reflect on the past, and make predictions about the future.

It also allows us to wander a mental landscape filled with emotional minefields, says Richard Davidson, a professor of psychology at the University of Wisconsin.

“It allows us to screw up our emotions far more than other animals,” he said during a visit to the University of Utah this week. “It allows us to persist in emotional responses beyond which they are still useful.”

Pioneer in emotions suggests training increases happiness

Deseret News (Salt Lake City)

Think of happiness as a skill, not so different maybe from learning to play the piano: the more you train, the better you get. That was the encouraging message Wednesday night from Richard Davidson, a pioneer in the biology of emotions.

Our emotions, it turns out, are revealed deep inside our brains, in areas such as the amygdala and the uncinate fasciculus. And these structures of our brain can physically change with training, says Davidson, who is a distinguished professor of psychology and psychiatry at the University of Wisconsin-Madison and is director of the school’s Waisman Laboratory for Brain Imaging and Behavior. He will also head up a planned Wisconsin Center on the Neuroscience and Psychophysiology of Meditation.

Paper firm exec to head UW-based bioenergy initiative

Capital Times

A Wisconsin paper company researcher has been chosen to head the Wisconsin Bioenergy Initiative (WBI), a public-private partnership formed to make the state a leader in developing clean, renewable energy.

Troy Runge, research director at Kimberly-Clark Corp., was announced as the director of WBI on Tuesday.

The U.S. Department of Energy selected UW-Madison in 2008 as the site of the Great Lakes Bioenergy Research Center, so the WBI is expected to be a catalyst in getting public and private ideas to move forward on clean energy.

Stem cell investment paid off for UConn (The New Britain, Conn. Herald News)

A 2005 decision to invest $100 million for stem cell research and training has paid off for University of Connecticut researchers and, Gov. M. Jodi Rell says, for the stateâ??s economy.

University of Connecticut researchers have created two new human embryonic stem cell lines essential for investigators working at the frontier of stem cell research. Discoveries can be translated into new treatments and cures for millions of people stricken with debilitating chronic diseases.

Tainted peanut products menace pets

MSNBC.com

Noted: Even if their pets show no signs of the illness, owners should always be careful. Researchers at the University of Wisconsin School of Veterinary Medicine said last year that they were able to easily isolate Salmonella spp. from healthy-looking dogs and cats, making them classic carrier animals.

â??Dogs and cats may suffer salmonellosis as a â??reverse zoonosis,â?? with infection transmitted from human-to-dog and subsequently back to other humans,â? the researchers wrote. â??Similarly, outbreaks of salmonella infections in large animal teaching hospitals have been linked to the introduction of bacteria from infected human personnel, with subsequent spread to animals and then back to other human workers.â?

New ALZ drug may yield big things

Wisconsin Radio Network

A UW-Madison scientist says “exciting” new research could pave the way for slowing or even stopping the onset of Alzheimers. Director of Alzheimer’s Research Dr. Sanjay Asthana says researchers are conducting studies with an experimental drug designed to stop amyloid protein from developing in the brain. Abnormal development of the protein has been linked to the disease’s progression.

Paper industry exec Troy Runge to lead Wisconsin Bioenergy Initative

Wisconsin Technology Network

Troy Runge, research director at Kimberly-Clark Corp., has been named director of the Wisconsin Bioenergy Initiative.

The initiative, a public-private partnership in bioenergy research, is based in the College of Agricultural and Life Sciences at the University of Wisconsin-Madison.

UW team finds key to Parkinson’s prevention

Capital Times

A University of Wisconsin-Madison research team has unlocked clues on how to possibly prevent Parkinson’s disease — by boosting a gene that prevents a toxic chemical from destroying neurons in a region of the brain that regulates movement.

UW-Madison pharmacy professor Jeffrey Johnson and colleagues Pei-Chun Chen, Marcelo Vargas and Delinda Johnson studied what effect boosting the Nrf-2 protein would have in blocking MPTP, a chemical that kills neurons in the substantia nigra region of the brain.

Face of space Tyson laments Americans’ scientific illiteracy

Capital Times

“There are six-and-half billion people on this planet, and there are 6,500 astrophysicists, so that makes each of us (astrophysicists) one in a million,” Tyson said Monday night at the Wisconsin Union Theater as part of the UW’s Distinguished Lecture Series.

….Tyson is the 21st century face of space, a mantle previously held by the late, great Carl Sagan. Tyson is director of the Hayden Planetarium and the host of PBS’ “NOVA ScienceNOW” program, aimed at educating a new generation of Americans in science.

And that is no small task.

Watchful waiting

Milwaukee Journal Sentinel

Quoted: Christopher Green, a pediatric pulmonologist at the University of Wisconsin-Madison.

Cash to cut carbon: UW offers $50K for top idea

Milwaukee Journal Sentinel

Could cold, hard cash help cut emissions of carbon dioxide and other greenhouse gases?

The Center for Sustainability and the Global Environment at the University of Wisconsin-Madison hopes so.

Modeled on the X Prize awards for technology innovations, SAGE today announced $50,000 in prize money in the UW Climate Leadership Challenge.

Profiting from Pluripotency (The Scientist, UK)

The Scientist

In April of last year, the US Food and Drug Administration invited three large biotech companies – Geron, Advanced Cell Technology, and Novocell – to testify about how to safely test human embryonic stem cell (ESC) products in patients. The science was discussed, recommendations were made, and, seemingly, everyone was on the same page toward moving ESCs into the clinic.

Rethinking UW support: Tom Still calls for building academic R&D

Wisconsin Technology Network

As economic news worsens and the projected state budget deficit grows, it’s increasingly unlikely that state government will begin to reverse the 25-year funding decline for the University of Wisconsin System in the next biennial budget. Nevertheless, Tom Still, president of the Wisconsin Technology Council, and others that tout the economic value of academic research and development say the Governor and lawmakers must do more than cut spending and raise taxes – they must figure out a way to stimulate economic growth. In this Visions interview with Still, he tells WTN that boosting university support and technology transfer is a demonstrated jobs creator.

Boosting protein protects against Parkinson’s disease: study (AFP)

Boosting the output of a protein produced by brain cells called astrocytes can provide complete protection from Parkinson’s disease, a study published Monday showed.

In the study, the results of which were published in the Proceedings of the National Academy of Sciences, researchers at the University of Wisconsin-Madison studied mice with astrocytes that produced twice the normal level of a protein called Nrf2.

Marshfield Clinic involved in study to test medical data-sharing

Wausau Daily Herald

Researchers at Marshfield Clinic want to speed up their understanding of rare diseases and find cures — by learning how to store, share and use medical records created by universities and clinics across the country.

The clinic, the University of Wisconsin-Madison and the University of Michigan are taking part in a pilot project led by Case Western Reserve University in Cleveland to test the effectiveness of a system. The group will share records on sleep disorders because diagnosing sleep apnea involves large amounts of data, said Dr. Justin Starren, who leads the Marshfield Clinic Research Foundation’s efforts to better apply information technology to health and medical research.

Professor makes physics fun (77 Square)

Say the word “physics” and the names Albert Einstein or Sir Isaac Newton might immediately pop into your mind. You might connect it to “rocket science” or just simply, “impossible.” Physics (or science in general) can be intimidating to both children and adults.

But UW-Madison professor Clint Sprott has been working over the last two decades to connect the word “physics” to “fun.”

Uw’s Herbarium Is A Flora Time Capsule

Wisconsin State Journal

Just a stone’s throw from UW-Madison’s seat of power on top of Bascom Hill is a place that melds old scientific methods with modern research that you likely have not heard of – The Wisconsin State Herbarium.

The herbarium in Birge Hall is a collection of 1.1 million dusty, dried plant specimens, taped or glued inside manila folders and tucked inside row upon row of huge, vertical metal file cabinets protected with insect traps. Boxes of overflowing specimens sit in the hallways.

UW bacteria study could provide clue to controlling pathogens

Milwaukee Journal Sentinel

Of the thousands of bacteria swimming inside you, relatively few are bent on destruction. Most busy themselves in a communal effort to keep you fit and free from disease – unless something changes.

Scientists have long wondered what causes harmful bacteria to cross the species barrier from animals to humans and what causes a good bacterium inside us to turn bad.

Now, researchers at the University of Wisconsin-Madison have discovered that a single gene can cause bacteria to change hosts. Light-emitting bacteria called Vibrio fischeri colonized pinecone fish, then jumped to the bobtail squid – all because of a regulatory gene, the scientists reported Sunday in the journal Nature.

TV and other factors lead to early teen sex: study (Reuters)

Too much television, low self-esteem, disappointing grades and poor family relationships can be a formula that adds up to early teenage sex, according to a new study.

“If you add up all the factors, you get a much more powerful predictor of who has sex and who doesn’t,” said Dr. Janet Hyde, of the University of Wisconsin, who headed the research team.