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Category: Research

Wisconsin stem cell patents upheld

Capital Times

The United States Patent and Trademark Office today upheld the final two stem cell patents taken out by the Wisconsin Alumni Research Foundation that had been challenged by foundations in California and New York.

The actions are the second time in two weeks that the patent office has supported the claims of key stem cell patents held by WARF, a private supporting organization of the University of Wisconsin-Madison. On Feb. 25, the office affirmed the claims of a third patent also relating to Dr. James Thomson’s work with human embryonic stem cells.

Government upholds WARF stem cell patents

Wisconsin State Journal

The federal government has upheld two more UW-Madison stem-cell patents, meaning all three such patents under contention can stand.

Expected appeals could linger for months or years, however, and the government review led the university to make a few changes to some patent claims.

More ethanol will expand Gulf of Mexico ‘dead zone’: report

CBC News

Ramping up ethanol production for alternative fuels will worsen the “dead zone” in the Gulf of Mexico, a stretch of water unable to support aquatic life, according to a report co-written by the University of British Columbia.

The U.S. Senate’s recently announced plan to triple production of ethanol made from corn starch by 2022 will increase the zone by 10 to 19 per cent from the 20,000-square-kilometres â?? an area roughly the size of New Jersey â?? it has recently occupied, the report said.

Biofuels will expand Gulf of Mexico dead zone – study (NEWS.com.au)

A PLANNED increase in US ethanol production from corn would spell environmental “disaster” for marine species in the Gulf of Mexico, said a co-author of a science study.

A boost in corn production will worsen the Gulf’s so-called “dead zone”, an area with so little oxygen that sealife suffocates, said Simon Donner, a geographer at the University of British Columbia in Canada.

Dr Donner and Chris Kucharik of the University of Wisconsin used computer models to conclude that growing enough corn to meet US biofuel goals set for 2022 would cause a boost of 10 to 34 per cent in nitrogen pollution in the Mississippi and Atchafalaya Rivers, which run into the Gulf of Mexico.

Green energy summit planned

Milwaukee Journal Sentinel

Helping reduce reliance on fossil fuels is expected to create jobs in the renewable energy sector as well as training opportunities for the state’s technical college system.

With that in mind, the state Technical College System and others will host a three-day Wisconsin Renewable Energy Summit beginning Wednesday at the Midwest Airlines Center in Milwaukee. Among the presenters will be UW-Madison’s Great Lakes Bioenergy Research Center.

Publication chronicles first 15 years of University Research Park

Capital Times

University Research Park in Madison announced Friday that it has published “The First Fifteen Years: 1984-1999” a retrospective about the award-winning research park.

The non-profit research and technology park was established in 1984 and now is home to more than 114 companies that employ more than 4,000 people. Many of the companies are the result of research done at UW-Madison. It contributes more than $680 million each year to the state’s economy.

Can drinking worm eggs treat MS?

Wisconsin State Journal

Some UW Hospital patients will soon test an unusual treatment: They’ll drink a cocktail of worm eggs, which will hatch inside their bodies.

Doctors say the low-grade infection of worms, harvested from pigs, can help regulate faulty immune systems. The patients have multiple sclerosis, in which the immune system attacks nerve cells.

UW doctors study rare-cancer drug

Wisconsin State Journal

Kyle Holen and Herbert Chen, doctors at UW Hospital, are studying an experimental drug that could someday give hope to patients with a rare form of cancer for which existing treatments rarely work.

The drug could treat neuroendocrine tumors, which involve cells that produce insulin, serotonin, thyroid and other hormones.

Controversial stem cell patent makes a comeback (New Scientist)

New Scientist

A key patent on human embryonic stem cells (ESCs) is back from the dead – in a form that seems less likely to stifle research.

James Thomson of the University of Wisconsin-Madison isolated the first human ESCs in 1998. This work and earlier experiments with cells from monkeys was covered by three US patents granted to the Wisconsin Alumni Research Foundation.

Remembering the Vilas Monkeys

WKOW-TV 27

A decade ago, a 150 rhesus monkeys from the Henry Vilas Zoo were shipped to Tulane University in New Orleans.

And, that’s where they died.

At the zoo Saturday a group of animal rights activists returned to remember the monkeys.

Curiosities: Varied water-air temps cause lake-effect snow

Wisconsin State Journal

Q. At what temperature does lake-effect snow happen?
— Submitted by Mason Rather, sixth grade, Jefferson Middle School

A. Lake-effect precipitation is driven by large temperature differences between cold air flowing over warm lake water, says Scott Bachmeier, a research meteorologist at the Space Science and Engineering Center at UW-Madison. The amount of precipitation depends mainly on the size of the water-to-air temperature difference and how far the wind blows across the lake.

UW-Madison professor fights cancer in her lab and life

Wisconsin State Journal

Patricia Keely is fighting cancer on two fronts:
â?¢ In her lab, she and her colleagues at UW-Madison are discovering secrets of breast cancer, including why it occurs more often in dense breast tissue.

â?¢ In her life, she volunteered for a clinical trial at the Mayo Clinic of a new drug in hopes of surviving her own cancer of the esophagus.

Mathematics Explains Mysterious Midge Behavior

New York Times

Hereâ??s a place thatâ??s unlikely ever to be a vacation spot for Yankee pitcher Joba Chamberlain: Lake Myvatn, in Iceland.

Myvatn, translating from Icelandic to English, means Midge Lake.

During mating season, the air at Lake Myvatn can also be thick with male midges, each hovering, waiting for a female to join him. â??Itâ??s a like a fog, a brown dense fog that just rises around the lake,â? said Anthony R. Ives, a professor of zoology at the University of Wisconsin.

Climate Study Links Atlantic Storms With African Dust Levels

Voice of America

Aided by satellite monitoring, scientists at the University of Wisconsinâ??s Cooperative Institute for Meteorological Satellite Studies have updated their study of cyclone formation in the eastern Atlantic Ocean off of Africaâ??s west coast. Their findings, released last moevels (Voice of America)nth, appeared about the same time as tropical Cyclone Ivan struck Madagascar in the Indian Ocean east of the African continent.

UW tries worm eggs to help MS patients

Milwaukee Journal Sentinel

For several years, scientists have suspected that our hyper-hygienic world of vaccinations, antibacterial soap and bottled water actually might be making some people sick by bewildering their immune systems and causing them to turn on their bodies.

Now, doctors at the University of Wisconsin-Madison are about to carry that theory to the ickiest extreme.

$20M lair for WARF rats

Capital Times

The UW Board of Regents today approved a land swap allowing construction of an underground holding facility for thousands of rats and mice for research use on the UW-Madison campus.

The project will be located in the 1200 block of Campus Drive at North Orchard Street, as part of the Wisconsin Institutes for Discovery, a biomedical research complex.

Approval of the land swap between the UW-Madison and the Wisconsin Alumni Research Foundation was needed so a $20 million plan that includes a receiving dock as well as the 10,000-square-foot “vivarium” — a facility for live animals for observation and research — could proceed.

Thomson stem cell firm signs deal with Roche unit

Capital Times

A company formed by UW-Madison stem cell pioneer Jamie Thomson today announced that it has entered into an agreement with Roche Palo Alto, one of pharmaceutical giant Roche’s five research facilities, to test candidate drug compounds for cardiotoxicity, or damage to heart tissue.

Under the agreement, Roche will supply Madison-based Cellular Dynamics International Inc. with two sets of 25 well-characterized drug compounds to validate CDI’s current toxicology products and services.

Bug study predicts irreversible changes of ecosystems (The Telegraph, UK)

The Telegraph (UK)

If you think there are too many midges in Scotland, try visiting Iceland where blizzards of the bugs form.

In the journal Nature, a team of ecologists from the University of Wisconsin, The University of Iceland and Royal Holloway, University of London, report on the flighty behaviour of algae munching midges in Iceland’s Lake Myvatn, which means “midge lake” in Icelandic.

Hey, express yourself, you’re in Wisconsin!

Capital Times

LAKE GENEVA — Stem cell researcher Jamie Thomson, conservationist Aldo Leopold, flamboyant Liberace. Visionary architecture, below-zero tailgating, cheese curds that squeak. House on the Rock, Taliesin, Harley.

Wisconsin is a place where you can feel free to be yourself and express yourself. This is the conclusion of a five-month branding project undertaken by the state Department of Tourism and announced Tuesday night by Gov. Jim Doyle at the annual Governor’s Conference on Tourism.

Nanotechnology research needs public support

Badger Herald

Better cancer treatment. Smaller, faster computers. Self-cleaning windows, even. This is just a small glimpse into the potential of nanotechnology, a science concerning the manipulation of materials at the molecular level. Sounds like a worthwhile project, right?

Groundbreaking Alzheimer’s Research Happening At UW Hospital

WISC-TV 3

MADISON, Wis. — Some groundbreaking research being done at the UW could greatly affect those at risk for Alzheimer’s disease.

The goal of the research is to try to identify Alzheimer’s disease before symptoms start occurring, and researchers believe to do that, you must look at the brain.

That’s exactly what Dr. Sterling Johnson is doing. He’s been doing work where healthy people, both with a family history of Alzheimer’s disease and without, have MRI’s done while performing memory tasks.

James Prudent: Biotech is more than just a good investment

Capital Times

In your Feb. 21 article titled “Challenges remain for biotech,” The Capital Times reviewed an interesting talk given at the University of Wisconsin last week by Steve Burrill, a venture capitalist who has created a very successful business focused on biotechnology investments. In the talk, Burrill presented his viewpoints on the biotech industry as an investment.

As a biotechnology industry advocate, scientist, and entrepreneur of over 20 years and as a father to three children, I found the article and Steve’s talk too pessimistic and narrow in scope.

Couple studies attitudes toward state’s wolves

Wisconsin State Journal

With wolves now roaming the state in greater numbers than anyone believed possible, their future is tied less to biology and the landscape than to public opinion toward a creature that is defined as much by myth as by science.

Adrian Treves knows this better than just about anyone.

Treves is a UW-Madison animal behaviorist and ecologist, and along with his wife, UW-Madison geography professor Lisa Naughton, has used extensive surveys to plumb public attitudes toward wolves in a deeper fashion than has ever been done before in Wisconsin.

Nanotechnology: the invisible frontier

Daily Cardinal

Whether it is actually used, the science is referenced in everything from state-of-the-art golf clubs to the iPod Nano. College kids and middle-aged corporate Americans alike are trying to tap into what the National Science Foundation predicts will be a one trillion dollar industry by 2015.

Good news for UW, state

Capital Times

The U.S. Patent and Trademark Office delivered some good news to the University of Wisconsin-Madison today (Thursday).

In dismissing a key challenge to James Thomson’s breakthrough discovery on stem cells by New York and California interests, the office cleared the way for the UW to benefit from the research in the years ahead.

Congratulations to the Wisconsin Alumni Research Foundation, which holds the patent, and Thomson, who pioneered the stem cell procedures. Not only will the school benefit, but so will Wisconsin taxpayers.

RFID may track, safeguard global blood supply (Computer World)

The global blood supply â?? going vein-to-vein, from donor to warehouse to hospital to patient â?? is tough to track. And tracking problems are part of the reason that thousands of bags of critically needed blood are thrown out every day.

Researchers at the University of Wisconsin-Madison are hoping to use radio-frequency identification (RFID) technology to create a way to better track blood supplies around the world. That, according to Alfonso Gutierrez, RFID lab director at the university, could lead to better handling and fewer instances of patients receiving the wrong blood.

A Disputed Patent on Embryonic Stem Cells Is Upheld

Chronicle of Higher Education

The U.S. Patent and Trademark Office has upheld one of the three disputed University of Wisconsin patents on a technique for isolating and maintaining embryonic stem cells. But the two groups that have challenged the patents say they will continue their efforts to overturn that patent, and the two other related ones.

US Upholds Key Stem Cell Patent (AP)

Philadelphia Inquirer

MADISON, Wis. – A federal agency has upheld a patent that covers embryonic stem cell research, rejecting a challenge from critics who say the patents are hindering research.

An examiner with the U.S. Patent and Trademark Office ruled this week that one of three patents can stand. A challenge to two other patents remains pending.

WARF stem cell patent upheld; fight to continue (Bizjournals.com)

Two consumer groups said Thursday that they intend to continue challenging three key human embryonic stem cell patents held by the Wisconsin Alumni Research Foundation after the U.S. Patent and Trademark Office upheld the validity of one of the disputed patents.

The decision was announced just a day after the International Stem Cell Forum in San Francisco, hosted by the California Institute for Regenerative Medicine, concluded Wednesday.

UW groups stem cell patent upheld

Milwaukee Journal Sentinel

Wisconsins role in the commercialization of embryonic stem cell research has received a boost from the U.S. patent office, which rejected a challenge to a key patent held by the Wisconsin Alumni Research Foundation.

Feds Uphold One Of WARF’s Key Stem Cell Patent

WISC-TV 3

MADISON, Wis. — Federal regulators are upholding a patent that covers embryonic stem cell research discovered at the University of Wisconsin-Madison.

An examiner with the U.S. Patent and Trademark Office said that one of three patents held by the Wisconsin Alumni Research Foundation (WARF) can stand. It hasn’t yet ruled on two others being challenged.

Critics had asked the patent office to throw out the patents, which cover discoveries made by UW-Madison scientist James Thomson. They argue the patents have hindered research in the U.S.

Group Releases Report On Women’s Health In Wisconsin

WISC-TV 3

MADISON, Wis. — The Wisconsin Women’s Foundation is releasing a first-of-its-kind report on Thursday that targets health concerns for women in Wisconsin.

The report targets more than 10 pressing issues related to women’s health. Dr. Teri Woods, of the University of Wisconsin School of Medicine, examined the results.

“I think if we look at areas of tobacco-use, alcohol, obesity, and if we look at sedentary nature of Wisconsin women we can go a long, long way in helping ourselves be strong and healthy,” Woods said.

WARF stem cell patent claim upheld by patent office

Capital Times

The Wisconsin Alumni Research Foundation has won a key patent battle for one of its stem cell patents, after the U.S. Patent and Trademark Office upheld the foundation’s claim to the patent.

The decision affirms WARF’s contention that an initial UW-Madison human embryonic stem cell discovery is a patentable invention.

The decision was announced in a press release this morning from WARF.

Feds Uphold One Of WARF’s Key Stem Cell Patent

WISC-TV 3

MADISON, Wis. — Federal regulators are upholding a patent that covers embryonic stem cell research discovered at the University of Wisconsin-Madison.

An examiner with the U.S. Patent and Trademark Office said that one of three patents held by the Wisconsin Alumni Research Foundation (WARF) can stand. It hasn’t yet ruled on two others being challenged.

Critics had asked the patent office to throw out the patents, which cover discoveries made by UW-Madison scientist James Thomson. They argue the patents have hindered research in the U.S.
The research foundation disputes that claim.

Group Releases Report On Women’s Health In Wisconsin

WISC-TV 3

MADISON, Wis. — The Wisconsin Women’s Foundation is releasing a first-of-its-kind report Thursday that targets health concerns for women in Wisconsin.

The report targets more than 10 pressing issues related to women’s health. Dr. Teri Woods, of the University of Wisconsin School of Medicine, examined the results and shared them with WISC-TV.

Americans Say ‘No’ to Nano

http://abcnews.go.com/print?id=4348729
If scientists could produce a tiny robot that could travel through your body and heal damaged tissue, eradicate disease-carrying microbes, and even wipe out a cancerous tumor, would you support their efforts?

Maybe not, especially if you are an American. Skepticism of experimental science is rampant, and scholars across the land are struggling to understand why, and what they can do to change attitudes. Studies sponsored by the National Science Foundation have found a widespread suspicion among the public that too many scientists are trying to “play God” by manipulating life, and that the government is inept when it comes to protecting its people.

“The United States is a country where religion plays an important role in peoples’ lives,” Dietram Scheufele, a University of Wisconsin-Madison professor of life sciences communication told participants at a recent meeting of the American Association for the Advancement of Science. “European countries have a much more secular perspective.”

Linda Baumann: Global health research good for us, world

Capital Times

The despondent faces of poor, sickly people in developing nations on our TV screens most nights can seem a world away from the majority of people of Wisconsin. But my work in some of the world’s most impoverished regions confirms that many of the diseases exacting a toll in Madison are decimating countries like Vietnam and Uganda.

One of the chronic diseases I’m most familiar with is diabetes, a condition once considered rare in the developing world. The incidence of diabetes is increasing in almost every corner of the world due to the same risk factors that we see in Western countries: obesity, poor nutrition and physical inactivity. By the year 2025, diabetes is expected to affect some 40 million, with 75 percent of cases occurring in developing countries.

(Linda Baumann is director of global health initiatives and a professor in the School of Nursing at the University of Wisconsin-Madison.)

Religion casts nanotechnology as immoral in U.S.

Capital Times

Americans distrust the morality of nanotechnology but Europeans have much more faith in the burgeoning science, according to a survey by a University of Wisconsin-Madison professor.

Dietram Scheufele, a professor of life sciences communication at the UW, says that is because religion exerts far more influence on public views of technology in the United States than it does in Europe.

Nanotechnology is a branch of science and engineering devoted to the design and production of materials, structures, devices and circuits at the tiniest possible scale, typically in the realm of individual atoms and molecules.

Scientists see huge potential for advances in computers, medicine and many other fields. But the survey of 1,015 adult residents of the United States found that only 29.5 percent found that nanotechnology was morally acceptable.

New job for cell scientist

Milwaukee Journal Sentinel

The Morgridge Institute for Research on Monday named stem cell pioneer James Thomson as director of regenerative biology and principal scientist.

Thomson Accepts New Role

NBC-15

A star UW stem cell researcher will play a key role at a new private research center in Madison.

James Thomson is named director of regenerative biology for the Morgridge Institute for Research being built on campus.

Thomson was first to isolate human embryonic stem cells in 1998. Last year, his team succeeded in turning skin cells into the equivalent of embryonic stem cells.

University leaders hope Thomson’s appointment will help recruit scientists to conduct breakthrough research.

Stem Cell Researcher Accepts Position At Institutes For Discovery

WISC-TV 3

MADISON, Wis. — A world-renowned stem cell scientist and researcher has accepted a key position with the Morgridge Institute for Research, the private, not-for-profit division of the Wisconsin Institutes for Discovery.

Jamie Thomson, the first member of the scientific team at the research facility, will be the director of regenerative biology. Thompson is currently a professor of anatomy at the University of Wisconsin-Madison School of Medicine and Public Health and will retain that position in addition to his new role. The announcement was made at a news conference at the UW Health Sciences Learning Center on Monday afternoon, WISC-TV reported.

UW’s James Thomson named to scientific leadership team

Capital Times

UW-Madison stem cell pioneer and researcher James Thomson is the first person to be named to the multidisciplinary scientific leadership team at the Morgridge Institute for Research.

The Morgridge Institute is the private, not-for-profit side of the Wisconsin Institutes for Discovery.

Thomson has accepted the position of director of regenerative biology and will become a principal scientist at the new institute, University of Wisconsin officials announced today (Feb. 25).

Study: Exercise increases breast cancer survival rate

Capital Times

Women who exercise after a breast cancer diagnosis can improve their chances of survival, according to a study by researchers at several universities and cancer centers, including UW-Madison.

The six-year study indicated women with breast cancer who engaged in moderate to vigorous exercise had a 35 to 49 percent decreased risk of dying from the disease. Women who had the most physical activity had higher survival rates than those with the lowest level.

A research team including investigators from the University of Wisconsin School of Medicine and Public Health made the findings in a study published in the February edition of Cancer Epidemiology Biomarkers & Prevention.

UW scientists find gene pathway

Wisconsin State Journal

The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies.

Oxidative stress chips away at healthy cells and is a process, scientists know, that contributes to a host of diseases and conditions in humans ranging from Alzheimer’s, heart disease and stroke to cancer and the inexorable process of aging.

A team of UW-Madison scientists has discovered a gene expression pathway that exerts a sweeping influence over this process of oxidative stress, which one day could allow for the manipulation of genes or development of new drugs to thwart disease.

UW-Madison professor teaches people to forgive

Wisconsin State Journal

For most of us, to say “I forgive you ” — and truly mean it — is an acquired skill.

“I think forgiveness absolutely has to be learned, ” said Robert Enright, a UW-Madison educational psychology professor who has studied the subject for more than 20 years. “Except maybe for the great saints of the world — and there aren ‘t too many of those. ”

Enright says forgiveness is one of the pillars of human moral development, and when practiced diligently can also be a pathway to better health.