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Category: Research

Minnesota researchers look to stem the tide of an uncertain future (Minnesota Daily)

On the 14th floor of Moos Tower, the laboratory appears ordinary. Researchers wear jeans, put plates under microscopes and record their observations. Also under their eyes is a controversy � cells that offer extreme hope to some and cause extreme apprehension to others.
The University�s Stem Cell Institute is at an important juncture in its brief existence, especially in the politically and morally contentious realm of embryonic stem cell research.

Stem-cell pioneer does a reality check (MSNBC.com)

MSNBC.com

MADISON, Wis. � Seven years ago, when James Thomson became the first scientist to isolate and culture human embryonic stem cells, he knew he was stepping into a whirlwind of controversy.

He just didn’t expect the whirlwind to last this long.

In fact, the moral, ethical and political controversy is still revving up ââ?¬â? in Washington, where federal lawmakers are considering a bill to provide more federal support for embryonic stem-cell research; and in Madison, Thomson’s base of operations, where Wisconsin legislators are considering new limits on stem-cell research.

Legislative panels OK cloning ban

Milwaukee Journal Sentinel

Madison – Legislative committees Tuesday approved a bill that would impose a comprehensive ban on human cloning.

The five Republicans on the Assembly’s Committee on Children and Families supported the bill, while two Democrats opposed it; one Democratic member wasn’t present for the vote. In the Senate’s Judiciary, Corrections and Privacy Committee, three Republicans voted in favor of the bill, while two Democrats voted against it.

U.W. Cattle Benefits Revoked

NBC-15

Two people working on cows at the U.W. get their care benefits retracted after ten beef cows die because of neglect.

A spokesperson from the College of Agriculture and Life Sciences says the cattle were fed poor quality hay and corn silage over the winter and were left malnourished. Six cows died of complications during birth and the other four died of malnutrition.

WisBiz People: UW Engineering Dean Says Tech Transfer is a Contact Sport

www.wisbusiness.com

Paul S. Peercy, dean of the UW-Madison College of Engineering for the past five years, likes to call technology transfer a ââ?¬Å?contact sport.ââ?¬Â

He doesn�t mean bruises and broken teeth, though, as in hockey or football. Peercy is talking about interdisciplinary research with scientists and engineers talking to each other at the earliest stages of product development.

Old Rennebohm not historic enough?

Capital Times

A proposal to give landmark status to the former Rennebohm’s drugstore at University and Randall avenues came in for tough sledding before the Madison Landmarks Commission.

The building at 1353 University Ave., built in 1925, is one of several in a run-down former commercial strip that would be demolished to make way for the first phase of the University of Wisconsin-Madison’s Institute for Discovery. Construction is tentatively scheduled to begin later this year.

Wiley: Cloning bill blocks research

Capital Times

A bill to make human cloning a crime in Wisconsin is nothing more than a “back-door attempt to criminalize embryonic stem cell research,” UW-Madison Chancellor John Wiley says.

“That’s the only reason I can think of for banning a tool that could be used for good or for ill,” Wiley told state lawmakers on Monday.

UW is wary of changes in patent law

Milwaukee Journal Sentinel

The head of Wisconsin’s biggest technology transfer organization has been in Washington, D.C., the last few weeks trying to temper enthusiasm in Congress for making big changes to U.S. patent law.

Carl E. Gulbrandsen, who testified at the invitation of House and Senate subcommittees, said the push to give courts more discretion about whether to grant injunctions in patent infringement cases could hurt organizations like his, which are trying to move technology out of university laboratories and into commercial use.

UW officials: Keep cloning an option

Wisconsin State Journal

Though no scientists are now cloning embryos at UW- Madison, university officials told legislators Monday that it is important to leave the research avenue open in order to study genetic illnesses and pursue potential cures.
Chancellor John Wiley testified before a legislative committee that is considering a proposed ban on all cloning. The ban would prohibit both therapeutic cloning, or cloning to create cells for research and medical treatments, and reproductive cloning, which is cloning to create an embryo that would result in a child.

GOP bills would ban human cloning

Milwaukee Journal Sentinel

Madison – Concerned that technology is outpacing ethics, Republicans in the Legislature are pushing a ban on human cloning, but critics say the move would block future research into genetic diseases.

The proposal is on a fast track. Identical bills – SB 243 and AB 499 – were introduced late Thursday, and Senate and Assembly committees will jointly hold a public hearing on the measures Monday.

Neglected cows at UW-Madison farm die

Wisconsin State Journal

Ten cows at a UW-Madison research farm died earlier this year after starving through two cold winter months, university officials said Monday.
The beef cattle were fed a diet of poor-quality hay and corn silage in late December and January that apparently left them thin and malnourished, said Ben Miller, assistant dean at the College of Agricultural and Life Sciences. Following the discovery of the cattle, the technician charged with caring for them has quit his post and a professor has been disciplined, he said.

Battleground between research, animal rights activists

Wisconsin State Journal

A shaky, amateurish video shows everything in graphic detail: Four masked people break into darkened university labs, pour toxic chemicals onto computers and stacks of files, and release hundreds of research rats and mice. They spray-paint walls with slogans such as “Science not Sadism” and “Free the Animals.”
The November break-in at the University of Iowa’s Spence Laboratories – a crime for which there have been no arrests but for which the group Animal Liberation Front, or ALF, has claimed responsibility – is characterized by university and law-enforcement officials as terrorism.

Debate Over Cloning Resurrects A Familiar Fight

WIBA Newsradio

UW Madison’s chancellor is warning of the impact of a proposal at the Capitol that would ban human cloning in Wisconsin. Chancellor John Wiley testified at a legislative hearing yesterdayââ?¬Â¦and he believes the measure would also ban embryonic stem cell research. (Additional UW-Madison items follow.)

Lifestyle link to Alzheimer’s strengthens

USA Today

Drinking vegetable juice, getting regular exercise, even brushing your teeth could offer protection against Alzheimer’s, a much-feared brain disease that affects 4.5 million people in the USA. Those and other findings were reported Sunday in Washington, D.C., at the first Alzheimer’s Association International Conference on the Prevention of Dementia.
Quoted: Mark Sager, a researcher at the University of Wisconsin-Madison Medical School

Doyle names members of biobased consortium

Capital Times

Gov. Jim Doyle has announced the members of the Consortium on Biobased Industry, which is charged with preparing a roadmap over the next year on how to best support the development of biobased products and energy in Wisconsin.

“In Wisconsin, we may not have oil fields,” Doyle said Friday. “But we can grow our own biobased resources. We will use these resources to produce renewable energy and value-added products, and reduce our dependence on oil.”

UW-Madison professors Charles Hill and Michael Sussman were among those appointed by the governor.

Man hikes 600 miles for cancer research

Capital Times

WAUSAU (AP) – A Madison man walking around the state to support a new University of Wisconsin-Madison cancer research building took a break in Wausau over the weekend before embarking on the second half of his journey.

Ron Reschke left his home in Madison on April 29 and since then has traveled more than 600 miles, stopping in La Crosse, Eau Claire, Ashland, Rhinelander and Merrill.

Bill angers stem cell scientists (AP)

Capital Times

Anyone caught cloning a human being in Wisconsin could face up to a decade in prison and a million dollars in forfeitures under a Republican bill that outraged stem cell scientists fear could handcuff their work in the state.

The measure would ban cloning to create babies. It also would outlaw so-called therapeutic cloning, a term for cloning human embryos for research such as extracting stem cells. Embryos are destroyed after taking out the cells.

The bill also would ban a practice called parthenogenesis, in which a female egg cell is stimulated to divide without fertilizing it.

Studies show healthful living can lessen Alzheimer’s risk

Milwaukee Journal Sentinel

Washington – Middle-aged sons and daughters of people with Alzheimer’s disease might be able to reduce their risk of getting the disorder through lifestyle measures such as exercise, avoiding gum disease, consuming alcohol in moderation, and drinking fruit and vegetable juices, according to new research from Wisconsin and elsewhere.

Still: Wisconsin can shine in the competitive biotech world, even among the giants

Wisconsin Technology Network

PHILADELPHIA ââ?¬â?? In 1996, the last time the Biotechnology Industry Organization held its international convention in Philadelphia, about 3,700 people attended. A decade later, BIO expects at least 18,000 convention-goers to descend on the City of Brotherly Love.

As much as city officials here may claim it�s all about their sprawling convention hall and other civic improvements, the size of the BIO 2005 crowd says much more about the growth of the global biotech industry.

Possible ban on human cloning?

Duluth News

MADISON, Wis. – Anyone caught cloning a human being in Wisconsin could face up to a decade in prison and a million dollars in forfeitures under a Republican bill that outraged stem cell scientists fear could handcuff their work in the state.

The measure would ban cloning to create babies. It also would outlaw so-called therapeutic cloning, a term for cloning human embryos for research such as extracting stem cells. Embryos are destroyed after taking out the cells.

GOP bills would ban human cloning

Milwaukee Journal Sentinel

Madison – Concerned that technology is outpacing ethics, Republicans in the Legislature are pushing a ban on human cloning, but critics say the move would block future research into genetic diseases.

Senate stem cell vote nears (Boston Globe)

Boston Globe

WASHINGTON — Senate majority leader Bill Frist is looking to schedule a vote next month on a controversial bill to expand federal funding of embryonic stem cell research, a move that could provoke President Bush to issue the first veto of his presidency.

Pros Visit UW for Sweet Truth about Candy

www.wisbusiness.com

MADISON ââ?¬â?? As a kid growing up on Long Island, Rich Hartel recalls that he could eat candy ââ?¬â?? any kind of candy ââ?¬â?? until he was ââ?¬Å?blue in the face.ââ?¬Â

ââ?¬Å?I even stole my dadââ?¬â?¢s licorice jellybeans, and I wasnââ?¬â?¢t that crazy about them,ââ?¬Â admitted Hartel, who is now a professor of food science in the College of Agricultural and Life Sciences at UW-Madison.

Editorial: Patients lose to politics

Capital Times

The state Assembly once again put politics above patients’ medical needs when members voted almost entirely along party lines Tuesday in favor of the so-called “conscience protection” bill, AB 207.

The legislation would allow health professionals, without fear of repercussion, to refuse to participate in procedures such as extracting embryonic stem cells for research or removing a feeding tube, if the action conflicts with their moral or religious beliefs.

Stratatech receives nearly $1 million | WTN

Wisconsin Technology Network

Madison, Wis. – Stratatech Corp. was awarded a federal Phase II SBIR grant of $922,000 from the National Institute of General Medical Sciences to further develop its engineered human skin products.

Established in 2000, Stratatech is based in Madison and employs 18 people, according to the 2005 edition of the Greater Madison Wisconsin Area Directory of High-Tech Companies. Its products are based on a source of pathogen-free human skin cells that are able to multiply indefinitely, a technology first identified at UW-Madison.

Stratatech receives $922,000 federal grant

Capital Times

Madison-based Stratatech Corp. has received a federal grant of nearly $1 million it will use to work to enhance the ability of its engineered human skin products to promote the healing of chronic wounds.

….Stratatech’s products are based on a patented, unique source of pathogen-free human skin cells identified at the UW-Madison as being able to multiply indefinitely.

Potential Landmark Could Complicate Plans for $375 Million Research Center

www.wisbusiness.com

Tear it down.

That�s what Steven Skolaski, president of the Rennebohm Foundation, will tell the Madison Landmarks Commission when it meets June 20 to consider preserving an 80-year-old former pharmacy at University and Randall avenues.

ââ?¬Å?I donââ?¬â?¢t know how I can be more plain than that,ââ?¬Â said Skolaski.

UW group contests patent law changes

Capital Times

Congress should leave the nation’s patent law alone, says the director of the Wisconsin Alumni Research Foundation.

Carl Gulbrandsen is in Washington today to testify on the Patent Act of 2005 before the U.S. Senate Judiciary Subcommittee on Intellectual Property. Gulbrandsen, who also serves on an advisory committee to the U.S. Patent and Trademark Office, spoke to the House Judiciary Subcommittee on Courts, the Internet, and Intellectual Property last week.

In that testimony, he said the proposed legislation “chips away at the value of university patents for the benefit of certain industries and, thereby, diminishes the good that can come from university technology transfer.”

Lake woes from fertilizer called worse (AP)

Capital Times

Farmers’ routine application of chemical fertilizers and manure to the land poses a far greater environmental problem to freshwater lakes than previously thought, potentially polluting the water for hundreds of years, according to new research.

In a paper published Monday in the Proceedings of the National Academy of Sciences, a University of Wisconsin-Madison expert blames the buildup largely on industrial agriculture’s excessive use of fertilizer and manure since the 1940s.

The concentration could cause the eutrophication of lakes for centuries as the treated soil slowly washes into lakes and streams, writes Stephen Carpenter, a professor of zoology and a leading expert on freshwater lakes.

Study: Phosphorus threatens Mendota

Wisconsin State Journal

The smell of Lake Mendota on some hot, humid summer afternoons is not something you are likely to read about in Madison tourism pamphlets.
The rank smell of weed and algae-choked shorelines belies the beauty of the blue lake as seen from a distance.

And now, a study from a UW-Madison limnologist shows that without aggressive steps to stem the flow of pollutants, especially phosphorus from fertilizers, into the lake, our legacy to future generations is probably going to be a lake as polluted or even dirtier and more weed-choked than it is today.

Division grows in stem cell debate

Milwaukee Journal Sentinel

One senator last week called it a “great national debate.” The battle over embryonic stem cell research may not rank with Iraq or the economy as a burning public concern. But it is fast becoming a fixture of the budget and culture wars in Washington, D.C., and state capitals across the country. Soon it may produce the first veto of the Bush presidency. It’s likely to play a role in the 2006 congressional campaigns, and it provides a clear fault line in Wisconsin’s hotly contested race for governor next year.

Doyle rips Republicans over stem cells

Duluth News

Gov. Jim Doyle blasted Republicans for threatening to pull state funding for stem-cell research and accused them of slashing money for public schools during a speech at the state Democratic convention in Oshkosh Saturday.

Ready or Not? Human ES Cells Head Toward the Clinic

Shortly before Congressman James Langevin cast his vote last month to relax federal rules on funding of stem cell research, the Rhode Island Democrat told his colleagues, “I believe one day I will walk again.” Langevin, who has been paralyzed since a gun accident at age 16, pleaded with his colleagues to vote with him. “Stem cell research gives us hope and a reason to believe. … We have a historic opportunity to make a difference for millions of Americans.”

CELL BIOLOGY: Ready or Not? Human ES Cells Head Toward the Clinic — Vogel 308 (5728): 1534 — Science

“The most sobering thing about [hES] cells is their power,” says neuroscientist Clive Svendsen of the University of Wisconsin, Madison, who works with both fetal and embryonic stem cells. The extreme flexibility and capacity for growth characteristic of ES cells makes them ideal for producing large quantities of therapeutic cells to treat, say, diabetes or spinal cord injuries. But these same traits also increase the risk that renegade cells could, as they have in animal studies, cause unwanted side effects, ending up in the wrong place or even sparking cancerous growth. “You have to learn to control that power in the dish” before thinking about putting the cells into patients, says Svendsen.

Stem cell expansion supported by UW scientist, urges senators to back bill

Capital Times

WASHINGTON – At the Senate’s first hearing Wednesday on a bill that would expand embryonic stem cell research, Dr. Su-Chun Zhang of the University of Wisconsin-Madison spoke in support of the measure, saying the United States was first to conduct breakthrough research on embryonic stem cells and shouldn’t be left behind.

“We Americans actually led the world by first establishing this human embryonic stem cell work. We should not be left out,” Zhang told the Senate Aging Committee. “The senators won’t let us down in leading the world in this area of promising research, which includes saving lives for all Americans.”

Zhang is a colleague of Dr. James Thomson, noted for founding the field of stem cell research at the University of Wisconsin-Madison.

Alzheimer’s drug firm takes top state award

Capital Times

Mithridion Inc., a Fitchburg-based company that is developing drugs to treat Alzheimer’s disease, has won the second annual Governor’s Business Plan Contest.
Mithridion, the top-scoring plan in the Life Sciences category, will receive $20,000 in cash and a year’s free rent at 525 Science Drive in University Research Park – an $80,000 value.

The firm’s co-founders are Jeff Johnson, an associate professor in the UW-Madison Pharmaceutical Sciences Division, and Trevor Twose, company CEO.

Let science pursue stem cell research

Wisconsin State Journal

A bipartisan consensus in favor of allowing scientists to pursue stem cell research is showing signs of exercising political clout in Madison and Washington.

Wisconsin should encourage this moderate coalition to grow so that it can fend off persistent efforts to block government funding for embryonic stem cell experiments.

At stake is not only the potential for medical advancements that could save lives but also Wisconsin’s potential to become a hotbed for stem cell research and the biotechnology industry that it could spawn.

Dr.Willy Wonka (Madison Magazine)

Madison Magazine

Not all of the research at the University of Wisconsin–Madison is in the hard sciences. Some of it’s fluffy, gooey, and even sweet.

Food engineering professor Richard Hartel studies chocolate under microscopes and teaches labs to make jelly beans. He’s also furthered UW’s longstanding involvement in the Institute of Food Technologists, a nonprofit dedicated to making food better. The organization has named him a 2005 fellow.

Stem cell ethics vary from abortion debate (AP)

The State (South Carolina)

At first glance, the nation’s emotional debate over stem cell research seems a mere rerun of the unending dispute over abortion. Both involve the questions about protecting the development of human life, after all.

But there are important moral and religious distinctions between the two issues, and some groups that oppose abortion are not offended by stem cell experiments — even though they necessarily destory human embryos.

Tom Still: With ethics guidelines, political consensus emerging on stem-cell research

www.wisbusiness.com

MADISON ââ?¬â?? In the halls of Congress as well as the Wisconsin Legislature, it is becoming more difficult for the opponents of human embryonic stem cell research to persuade fellow lawmakers that such science is unethical.

The fight over stem-cell research is far from over, but public opinion about its relative merits is beginning to carry more weight.

Don’t rush to put limits on stem-cell research

La Crosse Tribune

There are two proposals at the state level to limit stem-cell research. Legislators would be wise not to rush to enact them in the budget process. We could end up severely limiting Wisconsin’s ability to do research and compete economically.

State Sen. Scott Fitzgerald, R-Juneau, co-chairman of the Joint Finance Committee, says he wants to ban the use of state resources for embryonic stem-cell research.

Fledgling business working on keeping veggies fresh

Milwaukee Journal Sentinel

Middleton – A grocer who can put more vegetables into customers’ shopping carts and fewer in the Dumpster because they’ve spoiled is going to make more money.

That’s the basic marketing message for Nutra Park Inc., a young business that has turned a discovery made by a professor at the University of Wisconsin-Madison into a commercial product.

Panel of 2 minds on stem cells

Milwaukee Journal Sentinel

Madison – The Legislature’s budget-writing panel Friday sidestepped a proposed prohibition of the use of state resources for embryonic stem-cell research, and approved initial funding for a major biotechnology research facility where such research would be conducted.

Animal rights museum, primate labs to be neighbors (AP)

Chicago Sun Times

MADISON, Wis. — A pair of animal rights groups are working to open a museum detailing primate suffering between two primate research labs at the University of Wisconsin-Madison, saying it will serve as a constant reminder of the horrors of animal research.

UW-led team advances tiny tech

Capital Times

A UW-led team of international researchers has found a way to get extremely small materials to assemble themselves into patterns for use in electronic circuits.

The finding is important because electronics must be built on an ever-smaller scale, especially if they are to be used in the rapidly growing field of super-small nanotechnology.

The team, led by UW-Madison Prof. Paul Nealey, reported today in the journal Science that it can show how to create complex patterns vital in the production of nanoelectronics.

Corpse flower set to bloom (AP)

Capital Times

“Big Bucky” is back.
The rare, big and extremely stinky flower that caused a sensation at the University of Wisconsin-Madison when it last bloomed in 2001 could become the world’s largest flower when it blooms again next week.

The titan arum stood at 6 feet 4 inches Thursday in a UW-Madison greenhouse, on pace to rival the world record for cultivated flowers when it blooms and releases its trademark roadkill scent in the coming days.