From the national election to State Street’s 12-hour shutdown, these are the top stories of 2004-’05
Category: Research
Science gurus elect 72 new members
The National Academy of Science announced the election of 72 new members to the group Tuesday, including 19 women, the largest number of females ever elected to the NAS.
A bitter pill for older patients
Excluded from drug trials, the elderly face unknown risks.
Quoted: Alta Charo, UW-Madison professor of medicine and bioethics.
Massachusetts firm to buy UW spinoff Bone Care for $600 million
Madison, Wis. ââ?¬â? Massachusetts-based Genzyme Corp. said on Wednesday it has agreed to buy Bone Care International, a University of Wisconsin-Madison biotech spinoff, for $600 million in cash.
Panel Would Entrust Stem Cell Research to Local Oversight (Science)
The National Research Council and the Institute of Medicine this week called for the creation of a new layer of oversight at institutions where research on human embryonic stem (ES) cells is conducted.
UW-Milwaukee grant to start new institute
Continuing in a trend of academic expansion, Gov. Jim Doyle, University of Wisconsin-Milwaukee Chancellor Carlos E. Santiago and Aurora Health Care President Ed Howe announced the creation of the Wisconsin Institute for Biomedical and Health Technologies.
Through a $1 million UWM-provided seed grant, the WIBHT will involve the support of six schools and colleges and 65 researchers from UWM and Medical College of Wisconsin, according to a release.
Losing Sleep: Mutant flies need less shut-eye: Science News Online, April 30, 2005
Most people require about 8 hours of sleep a night, but some lucky oddballs function well on 4 hours or even less. A new study in fruit flies provides evidence that genetics plays a strong role in determining who can get by with little rest. A single mutation in a gene that’s also found in people can reduce the insects’ sleep needs by about two-thirds.
Chimeras on the Horizon, but Don’t Expect Centaurs
Common ground for ethical research on human embryonic stem cells may have been laid by the National Academy of Sciences in the well-received guidelines it proposed last week. But if research on human embryonic stem cells ever gets going, people will be hearing a lot more about chimeras, creatures composed of more than one kind of cell. The world of chimeras holds weirdnesses that may require some getting used to.
San Francisco: Stem cell’s Silicon Valley?
San Francisco has grabbed the lead among California cities battling for the state’s new embryonic stem-cell research headquarters, a $3 billion program that could fuel creation of biotechnology’s version of Silicon Valley.
UW’s Wiley attends political fundraiser
University of Wisconsin-Madison Chancellor John Wiley made a guest appearance at a political fundraiser on Thursday night for a Brookfield Republican.
Sen. Ted Kanavas’ campaign held the $100-per-person cocktail reception at the Madison Club, with information technology as the theme. Wiley’s special assistant, Casey Nagy, said the chancellor wanted to attend because it would be an opportunity to meet many people in the field of technology and venture capital.
Wiley would not make an endorsement or give any money at the event, Nagy said.
Nanotechnology report
Outline of the recommendations contained in the “Report of the Madison Area Citizen Consensus Conference on Nanotechnology.”
Nano-sized, huge impact on society
A group of Madison area citizens has leaped ahead of the latest technological revolution – nanotechnology – previously the realm of researchers and science fiction books such as Michael Chrichton’s scary “Prey.”
….Members of the citizens group who spoke during a press conference at the State Capitol on Thursday included Gail Vick, 52, of Madison, a manager in a corporate computer technology customer service area.
“I feel very privileged to have taken part in this innovative model for connecting ordinary citizens with the potential outcomes of scientific research that will undoubtedly affect our lives and the lives of our fellow world citizens in many ways,” she said.
Pioneering prof, Botox pioneer dies
Retired professor Ed Schantz, the grandfather of what are now known as Botox treatments and an expert in growing the world’s deadliest poisons, has died at age 96.
Schantz died Thursday, said Joe Donovan, a spokesman for Wisconsin Superintendent of Public Instruction Elizabeth Burmaster, one of Schantz’s four daughters.
Illustrations of rare bird turn up at UW-Madison
MADISON ââ?¬â? Robin Riderââ?¬â?¢s search for the elusive ivory-billed woodpecker led not through the swamps of Arkansas but among the rare natural history books at the University of Wisconsin-Madison.
The result? Several startling images of the bird whose rediscovery in Arkansas has electrified the birding world because it was believed to have gone extinct decades ago.
Carlos Santiago: Economic shifts hold potential for region
As America’s economy continues shifting from one that is predominantly manufacturing to one primarily knowledge driven, Wisconsin must remember the lessons it learned more than 100 years ago.
That was when the Industrial Revolution changed our economy from being based in agriculture to one based in manufacturing.
A woman’s place in the lab
MADISON, Wisconsin — The electrical and computer engineering department at the University of Wisconsin at Madison had a lackluster record on gender equality for many years.
In the late 1980s, a curmudgeonly male colleague locked the department’s only female professor out of her lab, and no one in the department intervened until she appealed to senior campus administrators. Over the next dozen years, the department of 40 to 50 people hired only four more women, and two of them left before tenure.
UW has goodly supply of ivory-billed woodpeckers
The researchers who rediscovered the ivory-billed woodpecker slogged through a swamp in Arkansas to find the legendary bird, last glimpsed deep in a Louisiana bottomland forest in 1944.
Thursday morning, Robin Rider stalked the woodpecker on the UW-Madison campus and, to her delight, found several. And she didn’t even get her feet wet.
Public Shouldn’t Be Left Out Of Review Sessions
This responds to Eric Sandgren’s April 23 guest column quarreling with suggestions that the UW-Madison is “deliberately secretive” regarding its use of animals in research. As a reporter who has covered this issue for Isthmus, I would like to bring a few facts to your readers’ attention.
Until August 2003, members of the public were able to attend the meetings of UW-Madison committees at which the protocols of animal experiments are reviewed, in accordance with federal law. This policy was abruptly changed, and now the public is excluded from this portion of the meetings.
Report urges caution with nanotechnology
A group of local residents Thursday presented state legislators with a report calling for caution in the development of nanotechnology.
The emerging field of nanotechnology is based on the manipulation of materials that can be as small as atoms, and is expected to have a profound impact on the nation’s economy in the years to come.
The report, which was sponsored by UW-Madison with help from the Center for Democratic Action in McFarland, sought to give ordinary citizens a chance to consider the promises and perils of technologies that will have a major effect on their lives.
Guidance on stem cells
By their very nature, science and technology are always in the fast lane while ethics usually runs a distant third. But that hardly means ethical considerations should be given short shrift. Without some value system in place, there is a very real danger that science can quite literally run amok, reined in only by practical and, worse, mercenary considerations.
Biomedical institute to bridge researchers, companies
The University of Wisconsin-Milwaukee is expected to announce today that it is making a $1 million seed grant for a biomedical research institute that will bring together 65 researchers from the university and the Medical College of Wisconsin.
Technology report pioneers citizen participation
Thanks in part to the efforts of UW-Madison professors and students, a group of citizens held a press conference at the capitol Thursday to present recommendations on the development of nanotechnology after spending a month learning about the rapidly advancing field and discussing it among themselves and with experts.
Scientists discover how plants disarm the toxic effects of excessive sunlight (PhysOrg)
A newly discovered pathway by which cells protect themselves from a toxic byproduct of photosynthesis may hold important implications for bioenergy sources, human and plant disease, and agricultural yields, a team of University of Wisconsin-Madison bacteriologists announced Monday in the Proceedings of the National Academy of Sciences.
“We’ve discovered a pathway that cells use to turn on certain genes and respond to singlet oxygen,” says Timothy Donohue, a professor of bacteriology in the university’s College of Agricultural and Life Sciences and lead researcher on the paper.
Plant Gene an Aid for Alternative Energy (Sci-Tech Today)
Scientists at the University of Wisconsin-Madison have been able to trace the cellular pathways that make up a plant’s defenses.
“This finding should make it possible to modify plants and other photosynthetic cells to avoid the toxic effects of singlet oxygen, which could impact agriculture and the treatment of human and plant disease, and aid the effort to create alternative bioenergy sources,” said lead researcher Timothy Donohu
Flaws detected after TB infects 3 at Seattle lab (Seattle Times)
Three workers in a downtown Seattle research laboratory were infected with tuberculosis while working on a vaccine for the deadly disease, state officials say.
L&I and IDRI reported the incident to the University of Wisconsin, which makes the Madison chamber, as it is called. But officials there said they didn’t think it necessary to alert any of the other 15 to 25 institutions using the chamber. The chamber operates with a vacuum, so no germs should get out, said Todd Kile, shops manager for the University of Wisconsin’s College of Engineering.
Panel Would Entrust Stem Cell Research to Local Oversight (Science)
The National Research Council and the Institute of Medicine this week called for the creation of a new layer of oversight at institutions where research on human embryonic stem (ES) cells is conducted.
Wing ding: Ivory-billed woodpecker, thought extinct, sighted in Arkansas
Quoted: Stanley Temple, a professor of wildlife ecology at the University of Wisconsin-Madison.
Stem-cell study grows too big for one department; UW builds collaborative programs | WTN
Madison, Wis. ââ?¬â? The University of Wisconsin-Madison is introducing two new stem-cell programs to lay the groundwork for future research and keep the university in a leading position.
Wide-eyed flies yield clues to genetic links to sleep needs (WSJ, 4-28-05)
Researchers at UW-Madison have found that help for those of us who have trouble sleeping may come from an unlikely source ââ?¬â?Ã? fruit flies, which are remarkably similar to humans when it comes to grabbing a few winks.
Gene found to dictate amount of sleep needed
While most of us can’t seem to function with less than seven hours of sleep, some people seem just fine with three or four. The difference, say researchers at the University of Wisconsin-Madison, is genetic.
Sen. Judy Robson: State-based research holds key to cures
“….Restricting stem cell research to existing lines will send the message that Wisconsin does not care about lifesaving research and is not interested in retaining its place as a leader in bioscience. It will weaken our efforts to retain a highly educated work force and discourage the best students and scientists from coming here.
“As a registered nurse, I firmly believe in pursuing the promise this research holds for preventing debilitating diseases, easing suffering, and preventing premature death….”
UW to add two new stem cell programs
The University of Wisconsin-Madison has announced it will add two new stem cell programs.
Clive Svendsen, a professor of anatomy and neurology, said on Tuesday that UW-Madison will add a regenerative medicine program and an interdisciplinary postdoctoral program that will advance stem cell research. He made the announcement at a meeting of stem cell researchers.
Government group announces research guidelines
Scientists who research embryonic stem cells may face increased regulations under new guidelines announced Tuesday by the National Academy of Sciences.
Group of Scientists Drafts Rules on Ethics for Stem Cell Research
Citing a lack of leadership by the federal government, the National Academy of Sciences proposed ethical guidelines yesterday for research with human embryonic stem cells.
UW creating 2 new programs
The University of Wisconsin-Madison is establishing two new stem cell programs – a regenerative medicine program, which will draw on faculty from the Medical School and the Wisconsin National Primate Research Center, and an interdisciplinary postdoctoral training program funded by a $1 million grant from the National Institutes of Health.
Panel urges national standard to govern stem cell research
A National Academy of Sciences panel Tuesday called for national oversight of human embryonic stem cell research.
Panel issues guidelines for stem cell research
Concerned about inadequate regulation of privately funded human embryonic stem cell research, a panel at the National Academies issued guidelines Tuesday for American scientists, universities and private institutions. “We know this research is going to occur,” said Norm Fost, a medical ethicist at the University of Wisconsin-Madison and a member of the academies’ advisory panel, so, “how do we make sure it gets done ethically?”
Beyond fun and games
Mark Twain defined work as that which a person is obliged to do, and play as that which a person is not obliged to do. But two UW-Madison researchers suggest that with job-specific video games, work and play don’t have to be at odds.
Jim Gee, a professor of education, and Kurt Squire, an assistant professor of education, argue that video games can teach players an array of important skills, such as how to think strategically, make quick decisions, cooperate and learn from their mistakes – all skills that employers demand.
Experts outline stem cell guidance
The scientific community would more closely regulate human embryonic stem cell research under guidelines released this morning by the National Academy of Sciences.
Two University of Wisconsin-Madison science ethicists, Norman Fost and Alta Charo, participated in the formation of the guidelines. The academy is trying to assuage public concerns about stem cell research, as well as to create uniform codes of ethics for all institutions. The guidelines also cover cloning.
We can’t help but watch the game-blame nature
After the Boston Red Sox won the World Series last October, a Boston friend told me he rode an emotional high for weeks, and even now feels a rush of exhilaration when he recalls the victory.
Protein may prevent brain diseases
Shedding new light on brain-related diseases, UW-Madison scientists Jeffrey Johnson and Marcus J. Calkins have discovered a way to “re-engineer” the brain that may defend against such diseases as Alzheimer’s, Parkinson’s and Huntington’s diseases. Johnson’s team is pioneering a procedure that prevents oxygen from building up to toxic levels in the brain.
Professor devises new plan to seek evidence of cougars
We last left Eric Anderson as he got ready for a research project to prove that cougars once again roam parts of Wisconsin. Over the winter, he and students from the University of Wisconsin-Stevens Point spent 100 hours on weekends looking for the big cats near purported hotspots such as Rhinelander, Tomahawk and Vilas County.
Human brain’s ‘creative neurons’ focus of talk
Mozart’s creativity led him to compose magnificent symphonies. Shakespeare’s creativity inspired him to write timeless plays. Einstein’s creativity helped him formulate a revolutionary vision of the universe.
Sandgren: Public does know about university research
The use of animals in research is a socially sensitive issue. The tension between opposing perspectives hinges on the following fact: Certain questions about human and animal health can only be answered through animal studies. No animals, no answers. In this context, “alternatives to animal studies” means asking different questions.
As a large research university, UW-Madison is a magnet for animal rights activists. And this year we have a bumper crop. They are busy dumpster diving, video taping university research facilities and doing their best to intimidate researchers and staff. They also are proving to be artful propagandists.
UW scientist evolves into known author
Like Rudyard Kipling, only in a lab coat, Sean Carroll has for years been telling us how creatures such as butterflies get their spots.
Carroll, a molecular biologist with the Howard Hughes Medical Institute on the UW-Madison campus, has published a steady stream of journal articles detailing the invisible workings of genes that power the adaptation and evolution of all animals — the genes, for example, that help a butterfly camouflage itself from predators with different colors or colorful eyespots.
Ready, set, grow
What’s an eager Wisconsin gardener to do in late April when it’s too cold to plant tomatoes?
Consult the experts Saturday at the first Family Horticulture Day at UW-Madison’s West Madison Agricultural Research Station.
UWM fills research development post
The University of Wisconsin-Milwaukee decisively advanced its aspirations to become a nationally recognized research school with the announcement Thursday that it hired a technology entrepreneur with a broad international background for a newly created vice chancellor post. The school hired Abbas Ourmazd, an Iranian-born U.S. citizen who worked for Lucent Technologies’ Bell Labs in the U.S. before taking on a leadership position with the German national technology labs, as UWM’s first-ever vice chancellor for research.
Experts: U.S. behind in stem cell research
Despite the medical promised of human embryonic stem cells, the U.S. is falling behind other countries in such research because of government restrictions on the use of the controversial cells, according to speakers Thiursday at the fourth annual International Bioethics Forum.
Amended bill to hurt stem-cell research
It seemed like Wisconsin was going to stick to its progressive tradition. Although President George W. Bush had enacted a policy on stem-cell research prohibiting federal funding for the acquisition of new embryonic stem-cell lines, Wisconsin had taken it�s own steps to advance the science. Via actions such as Gov. Jim Doyle�s fiscal commitment to embryonic stem-cell research in his most recent budget, the state seemed to support the study of embryonic stem cells. Unfortunately, just as things were looking up for embryonic stem-cell research in Wisconsin, proponents of the research hit a roadblock.
Feinstein, other senators renew stem cell push
WASHINGTON – Sen. Dianne Feinstein and a bipartisan group of colleagues renewed efforts Thursday to expand embryonic stem cell research, introducing legislation that would allow federal support for such research to be used in treating disease.
Researcher to Seek Clinical Trial on ALS
MADISON, Wis. — A University of Wisconsin-Madison researcher said he would ask federal regulators Friday to approve the first clinical trial injecting special stem cells into the spinal cords of people with the degenerative nerve ailment called Lou Gehrig’s disease.
WARF suit says firm violated contract
The Wisconsin Alumni Research Foundation, the technology transfer and licensing arm of the UW-Madison, has filed a lawsuit against Xenon Pharmaceuticals Inc., charging it with breach of contract and other violations of its agreement with WARF.
Attorneys for WARF said the suit, filed Wednesday in U.S. District Court in Madison, seeks to ensure that the interests of UW-Madison and its inventors are protected and that WARF receives its contractual share of a $157-million agreement entered into by Xenon, which is in British Columbia, Canada.
UW-Madison rat experiment could lead to stem-cell treatment for ALS
Madison, Wis. ââ?¬â? Scientists at the University of Wisconsin-Madison have sucessfully injected stem cells into rats’ spines in a way that could lead to treatments for degenerative diseases ââ?¬â?? but they did not use the controversial embryonic stem cells.
GOP deserves rebuke for restricting science
Assembly Republicans ought to be embarrassed by the mess they made of a bill to encourage businesses to create research-related jobs in Wisconsin.
The Assembly last week passed the bill, to offer businesses tax credits for conducting research and development, but only after attaching an amendment to withhold the credits from businesses focusing on human cloning or research into new lines of human embryonic stem cells.
Stem Cells to Treat Lou Gehrigs Disease (WPR)
(MADISON) University of Wisconsin researchers have created a new kind of stem cell that may eventually be used as a drug delivery device to treat Lou Gehrig�s Diseas. (Third item.)
UW stem cell research targets ALS
Scientists at UW-Madison say they may be within two or three years of human trials on a promising stem-cell treatment for the deadly nerve disease amyotrophic lateral sclerosis or ALS.
In an article published Tuesday in the journal Human Gene Therapy, researchers reported they have injected ALS- afflicted rats with human nerve stem cells that flourished in the animals’ diseased spinal cords.
UW takes ‘nice step’ in Lou Gehrig’s disease research
Scientists at the University of Wisconsin-Madison have found a way to insert healthy neural stem cells into diseased rats, and keep those cells alive.
The rats were afflicted with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. The researchers successfully transplanted genetically modified neural stem cells into a rat’s spinal cord and kept the stem cells alive, releasing a neuron-protecting protein.
Stem Cell Discoveries, Laws and Debate
Madison: UW stem cell researchers have announced a major breakthrough in the treatment of ALS, or Lou Gehrig’s disease. ALS causes motor neurons to die and slowly paralyzes its victims.
Race to Human Stem-Cell Trials (Wired News)
SAN DIEGO — Several scientists have used embryonic or fetal stem cells to help rodents with spinal cord injuries walk again. The researchers travel the country showing videos of rats dragging their hind legs, followed by clips of them miraculously hopping around following stem-cell injections
Rain threatens lakes
To the untrained eye, it looks like a peaceful creek. But the water flowing through the UW Arboretum’s West Wingra Marsh is a deep gully cut by unmanaged storm water.