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Category: Research

Competition for stem cell research is fierce

Wisconsin Technology Network

While Wisconsin�s position in stem-cell research is strong, there are pitfalls and competitors to reckon with if the state wishes to hold its leading position, according to UW-Madison stem cell researcher Prof. Gabriela Cezar.

Cezar, who recently joined UW to assist with its stem-cell work, spoke this week at a luncheon sponsored by the Wisconsin Innovation Network, a division of the Wisconsin Technology Council, about the current state of stem-cell technology and where the field can go in Wisconsin and worldwide.

Kidney Disease on the Rise (WPR)

Wisconsin Public Radio

(MADISON) Kidney disease is sharply increasing in Wisconsin. One reason may be the increasing lifespan of residents. It was the focus of a study done by the Population Health Institute at the University of Wisconsin-Madison.

UW researcher says Wisconsin set to capitalize on stem cell boom (wisbusiness.com)

A top UW-Madison researcher who has worked for the Pfizer drug company said Tuesday that firms using stem cells to test and create new drugs could generate more than $3.6 billion in revenues by 2020.

And Wisconsin could be home to new companies doing doing that work, thanks to a wealth of scientific experts here, said Dr. Gabriela Cezar, who spoke at a Wisconsin Innovation Network luncheon.

WisBusiness: UW researcher says Wisconsin set to capitalize on stem cell boom

www.wisbusiness.com

A top UW-Madison researcher who has worked for the Pfizer drug company said Tuesday that firms using stem cells to test and create new drugs could generate more than $3.6 billion in revenues by 2020.

And Wisconsin could be home to new companies doing doing that work, thanks to a wealth of scientific experts here, said Dr. Gabriela Cezar, who spoke at a Wisconsin Innovation Network luncheon.

Blastoff time for state?

Capital Times

Spaceport, spacecraft and other aerospace facilities in Wisconsin?

Yes, say legislators sponsoring a bill that would create a Wisconsin Aerospace Authority and authorize it to develop those facilities and related services. The bill also would give the authority the power of condemnation and authorize municipalities to develop and operate spaceports.

The authority would promote and provide public-private coordination for the aerospace industry in Wisconsin, according to the state Legislative Reference Bureau. Supporters envision a future for Wisconsin in space commerce and tourism.

The proposed authority would be a public body created by state law that is not a state agency, similar to the University of Wisconsin Hospitals and Clinics and the Wisconsin Housing and Economic Development Authority. It would be able to receive federal funds.

Light-detecting Protein Mapped

Wisconsin State Journal

In a move that could light up the future of agriculture, UW-Madison scientists have mapped the three-dimensional structure of a protein in plants that detects light.

Now that the structure of the protein, called phytochrome, has been detailed, researchers might be able to manipulate it to make crops more or less sensitive to light or make plants flower at different times of the year.

Start-up makes pitch to scientists

Milwaukee Journal Sentinel

NimbleGen Systems Inc., a 6-year-old company spun out of the University of Wisconsin-Madison, developed a gene chip that is used to identify how genes work. Management and the company’s investors say these gene chips have the potential to revolutionize genetic research.

$2.5 million to go to Institute

Badger Herald

Despite a longtime rivalry, Minnesota Vikings fans and Green Bay Packers fans found common ground last week. David Mandelbaum, an ownership partner of the Vikings, unveiled a monetary gift to bolster cancer research at the University of Wisconsin during last Monday�s game.

Bonding, brain chemistry linked (Los Angeles Times)

Los Angeles Times

Children adopted from abroad often have difficulties adjusting to their new families and to life in this country, exhibiting poor social skills, problems bonding with new family members and reticence in dealing with strangers.

Those difficulties are generally traced back to emotional deprivation in large orphanages, where infants often outnumber staff by 40 to 1, and caregivers do little more than feed and change the infants.

UW scientist finds a way to bring milk to the tropics

Milwaukee Journal Sentinel

A University of Wisconsin-Madison scientist has figured out what appears to be an economical way to solve the scarcity of milk in developing tropical countries. But it is more complicated than shipping a truckload of dairy cows south.

Brain Stents Used To Fend Off Strokes

Wisconsin State Journal

Dave Cooley was running a chainsaw in the woods near his western Wisconsin home when he suddenly lost strength in his arms and legs.

He sat on a tree stump for nearly half an hour before recovering.

“I lost my senses, and it took a long time to get my senses back,” said Cooley, a farmer from Bagley.

Wisconsin consortium aims for defense business

Wisconsin Technology Network

Congress has approved a $500,000 start-up grant for the recently announced Wisconsin Security Research Consortium, a non-profit group for classified, defense-related projects.

The consortium, led by the Wisconsin Technology Council, will also initially include the UW System, the Medical College of Wisconsin, the Marshfield Clinic Research Foundation, and the Milwaukee School of Engineering.

BellBrook fed grant for breast cancer work

Capital Times

The National Institutes of Health has awarded BellBrook Labs a $250,000 Phase I SBIR grant that will aid development of a microscale mammary tissue model to accelerate the understanding and treatment of breast cancer.

The work originates in the laboratory of Dr. David Beebe of the UW-Madison Department of Biomedical Engineering.

Exploring a Hormone for Caring

New York Times

The lack of emotional care given to infants in some Romanian and Russian orphanages has provided researchers an opportunity to study the hormonal basis of the mother-child bond.

Researchers led by Seth D. Pollak of the University of Wisconsin have found that these children, even three and a half years after adoption into Wisconsin families, produce two critical hormones in a different pattern from children with traditional upbringings.

Program May Reduce Drinking (Harvard Crimson)

Harvard researchers published a study last week concluding that cooperation between colleges and communities reduces binge drinking and drunk driving.

Three researchers at the Harvard School of Public Health (HSPH) found that schools that fully implemented the ââ?¬Å?A Matter of Degreeââ?¬Â (AMOD) approach prevented drunk driving more effectively than institutions that used traditional alcohol policies that focus on educating individuals.

Still: Animal testing: Beyond the protests, instances of mistreatment are rare

Wisconsin Technology Network

Madison, Wis. ââ?¬â?? At one level, itââ?¬â?¢s possible to understand why animal-rights advocates passionately oppose experiments involving animals. No one likes to see another creature suffer needlessly.

Beyond the passion, however, exist facts about animal-based research that run counter to the intimidating tactics of some protesters, such as those who recently targeted the homes of researchers in Madison. Information about the true extent of animal research ââ?¬â?? and its benefits for humans and animals alike — deserves to be heard above the bullhorns and protest signs.

A clue to why some adopted children can be anti-social

Wisconsin State Journal

At night, when Sue Hunt reads stories to her daughter Anna, the rambunctious 7- year-old squirms in bed, seemingly seeking affection but asking her mother to go away.
“She has this way of keeping you at arm’s distance, yet she needs you so bad,” said Hunt, of Madison.

Now UW-Madison scientists say they have found a biological clue to anti-social behavior in children such as Anna, who was adopted from a Russian orphanage.

A biological cause of behavior? (Newsday)

Scientists have found startling differences in a hormone linked to social bonding in children who spent their first years in foreign orphanages. These changes remain two years after they have gone from an environment of neglect to one of love and attention.

Crammed orphanages have lasting effects (Nature)

Nature

Children who were seriously neglected in infancy can carry a physiological burden for years, even after moving to a loving environment. A study of their hormonal responses shows that their brains are less equipped to trust and form social bonds than other children.

“We don’t want to reach the conclusion that this difference is permanent,” says Seth Pollak, a developmental psychopathologist at the University of Wisconsin, Madison, who led the study. But he adds that the take-home message is that “children really need to be in families”.

Agitating for a regional revolution

Milwaukee Journal Sentinel

Significant research and development activity and a fair number of start-ups have failed to spark any critical mass of emerging technology industries in the Midwest, according to a report by an economist with the Federal Reserve Bank of Chicago. Also quotes Allen J. Dines, assistant director of the University of Wisconsin-Madison Office of Corporate Relations, and Andrew Cohn, spokesman for the Wisconsin Alumni Research Foundation.

Demonstrators Protest In Front Of Wrong House

Wisconsin State Journal

Demonstrators discovered this week that targeting researchers at their homes has potential pitfalls.
A group protested for 45 minutes Tuesday night outside what they thought was the home of UW Medical School assistant professor Michele Basso.

UW pediatrician wins award

Badger Herald

University of Wisconsin pediatrician Bruce S. Klein has been awarded the National Institutes of Health�s Method to Extend Research in Time award, which will fund his research for 10 years, officials announced Monday.

As Earth warms, health risks grow

Milwaukee Journal Sentinel

Add one more item to the list of things that can be affected by climate change and global warming: human health.

Researchers at the University of Wisconsin-Madison and the World Health Organization have compiled a series of studies showing that people have been adversely affected by regional and global climate change. The WHO suspects 150,000 people per year, for the past 30 years, have died as a result of a gradually warming planet. The WHO says that annually, 5 million cases of illness can be attributed to it, too.

Grant to help state gain research funding

Capital Times

A $500,000 federal grant is aimed at helping Wisconsin gain more funding for classified and sensitive research. The grant is to the non-profit Wisconsin Security Research Consortium, which was launched this fall by the Wisconsin Technology Council and 11 public and private academic research partners.

The grant is earmarked for the consortium’s start-up, administrative and research work, not for individual companies.

The initial members of the Wisconsin Security Research Consortium are the UW System, UW-Madison, UW-Milwaukee, UW-Stevens Point, UW-Superior, UW-La Crosse, UW-Stout, UW-Extension, the Medical College of Wisconsin, the Marshfield Clinic Research Foundation, the Milwaukee School of Engineering and the Tech Council. The consortium will eventually include associate members from private industry.

Climate Shift Tied To 150,000 Fatalities (Washington Post)

Washington Post

Health and climate scientists at the University of Wisconsin at Madison, who conducted one of the most comprehensive efforts yet to measure the impact of global warming on health, said the WHO data also show that rising temperatures disproportionately affect poor countries that have done little to create the problem. They reached their conclusions after entering data on climate-sensitive diseases into mapping software.

Global warming poses ethical challenge: scientists (Reuters)

ABCNEWS.com

LONDON (Reuters) – Global warming poses an enormous ethical challenge because countries that produce the least amount of greenhouse gases will suffer the most from climate change, scientists said on Wednesday.

Whether it is an increase in poor health from diseases such as malaria or shrinking water supplies, nations in sub-Saharan Africa, Asia and South America are vulnerable to the consequences of changes in global temperatures.

UW report highlights global warming deaths

Wisconsin State Journal

Global warming, which scientists say is causing higher temperatures, rising sea levels and more droughts and floods, is also killing 150,000 people each year, a UW-Madison research review finds.

The review includes an assessment in 2002 by the World Health Organization.

Doyle: Standing up for stem cell research

Wisconsin Technology Network

Diseases like Parkinson’s, Alzheimer’s, juvenile diabetes and spinal cord injuries affect millions of American families – including my own. Stem cell research, which is being pioneered in Wisconsin, may one day offer a cure to some of these diseases. But these cures will continue to elude us if we allow partisan political ideology to get in the way of the vital work of scientists.

Bill would help professors profit

Capital Times

A bill that would make it easier for University of Wisconsin professors to cash in on their research is part of a package of “Invest Wisconsin” legislation announced by Republican legislators today.

Other laws – some already introduced and others to come – would create wide-ranging tax credits and exemptions aimed at promoting investments in high-technology projects and businesses.

Top House Democrat unveils energy plan

Milwaukee Journal Sentinel

Rep. Tammy Baldwin, a Democrat from Madison, said the plan was “necessary if the United States is to maintain a leadership role in technology and grow our economy in the 21st century.”

Baldwin said that “if the Congress adopts this agenda, both the UW-Madison and area businesses will surely benefit from increased federal support for research and development in alternative energy sources, high speed communications and biotechnology.” The University of Wisconsin-Madison was the fourth-biggest research institution in the country in fiscal 2003, according to National Science Foundation figures.

Start-up biotech firm stems from TechStar

Capital Times

MatriLab, a biotech start-up company with one foot in Madison and the other in Milwaukee, is part of the new “tech corridor” taking shape between the two cities.

Basic scientific research is being done at UW-Madison, while clinical work is taking place in Milwaukee.

The company, which makes an innovative drug delivery product for wounds, stems from a partnership that includes scientists, clinicians and management consultants.

UW professor earns top science honor

Capital Times

A University of Wisconsin-Madison professor has won the National Medal of Science, the nation’s highest honor for science and technology.

Edwin Lightfoot, emeritus professor of chemical and biological engineering, is one of eight recipients of the award, which will be presented by President Bush in a White House ceremony. The date has not yet been set.

Lightfoot joined the faculty at UW-Madison in 1953. His textbook, “Transport Phenomena,” published in 1960, is considered a landmark in chemical and biological engineering.

A better way to quit

Wisconsin State Journal

Lynnae Meyer quit smoking last year – until a house fire forced her to move in with her mother, and the stressful situation led her back to cigarettes.

This year, the 28-year-old from Mineral Point decided to quit again. She had developed bronchitis, and with a family history of cancer, she worried that poor health could keep her from caring for her 6-year-old son.

“I was afraid I would never see my son graduate from high school,” she said.

Meyer is one of more than 300 people enrolled in one of the most comprehensive smoking cessation studies ever conducted at UW- Madison.

President Bush to award UW professor

Badger Herald

A University of Wisconsin-Madison professor was named a recipient of the 2004 National Medal of Science, the nation�s highest honor for science and technology, by President George W. Bush Tuesday.

Treatment Is ‘excessive’

Wisconsin State Journal

The Wisconsin State Journal’s Nov. 4 editorial “Extreme tactics miss the mark” is what misses the mark. The extreme tactics are not being perpetrated by animal rights activists; the extreme tactics are being perpetrated by the rest of us.

Reject Medical Advances?

Wisconsin State Journal

Animal rights activists have done little to evaluate the merit of research being done at our university, indicated by distortions in public statements. People who use animals for biological research are harassed, regardless of whether they have done anything reprehensible.

Most Are Outraged

Wisconsin State Journal

I participated in the recent demonstrations against the primate experiments at the UW. I was approached by many neighbors and passers-by who shared their experiences with me, involving the animal experimentation industry.

Intimidation Unreasonable

Wisconsin State Journal

Thanks to the Wisconsin State Journal for their balanced coverage of the recent protests. Too often the tactics of these groups, which include harassment, threats and property destruction, are underreported. The best way to expose the extremism of these groups is to fairly and openly document their methods.

Debate Not ‘stifled’ By Uw

Wisconsin State Journal

Activist Rick Bogle, in his Monday guest column, claims the UW stifles debate about animal research. His contention is easy to refute. As the chairman of the All Campus Animal Care and Use Committee, the oversight body for animal use at UW-Madison, I have been working to establish contact with animal activists to find common ground, improve research animal welfare and enhance public understanding.

Animal Research Essential

Wisconsin State Journal

A generation ago, childhood cancer was considered a death sentence. Now, through research, approximately 75 percent of children with cancer in the U.S. are being cured. Still, we need to provide more effective and less toxic treatments.
This means testing. Some research can be done by computer modeling and in test tubes. However, any experimental treatment being considered for clinical testing must first demonstrate conclusive anticancer effects without causing “side effects” that outweigh the anti-tumor benefits, which still can only be done by involving laboratory animals that have cancer, most often mice.

UW man in trenches of the bird-flu battle

Wisconsin State Journal

Not everyone can claim a chicken as a career counselor.
But sick chickens in Pennsylvania steered Yoshihiro Kawaoka into bird flu research.

As attention to the human threat of a worldwide epidemic from bird flu has swelled in recent months, the UW-Madison virologist has emerged as one of the country’s leading experts on the subject.

Feds want to limit access to research

Wisconsin State Journal

SAN JOSE, Calif. – New federal proposals would significantly change how research is conducted at universities, placing tough restrictions on foreign-born scientists and tightening access to equipment and computers.
UW-Madison researchers said the proposed rules could create problems for them. Universities are exempt from most federal controls on their work because they conduct what the government calls “fundamental research” – work that is taught in open classrooms, published in journals and shared openly with the scientific community.

Our Faith in Science

New York Times

SCIENCE has always fascinated me. As a child in Tibet, I was keenly curious about how things worked. When I got a toy I would play with it a bit, then take it apart to see how it was put together. As I became older, I applied the same scrutiny to a movie projector and an antique automobile.

UW fueling nuclear energy recycling

Daily Cardinal

Across the United States, radioactive uranium rods wait in storage containers at nuclear power plants, mounting into a large waste issue for the national government and utility companies. As waste builds, many Midwestern universities, including UW-Madison, are looking to improve nuclear fuel reprocessing techniques and streamline the nuclear fuel cycle, which would reduce the overall volume of toxic waste.

Waukesha area in top shape, UW study says

Milwaukee Journal Sentinel

Stay in school, kids – it’s good for your health.

That’s the premise of a study being released today that ranks Waukesha County as Wisconsin’s healthiest county, partly because of its low high-school dropout rate.

The theory behind the University of Wisconsin-Madison study is that educated people are more likely to make smart choices about cigarette smoking and other unhealthy lifestyles.